New study demonstrates superiority of vaginal estradiol tablets in improving quality of life, mood, and sexual function CLEVELAND, Ohio (May 9, 2018)–Sex shouldn’t hurt at any age, yet 75% of postmenopausal women report vaginal dryness, and up to 40% report pain with intercourse. A new study reports that vaginal estradiol tablets just might be what’s...
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For stroke victims, brain magnetic stimulation leads to improved walking speed
A technique of magnetic stimulation of the brain can increase walking speed in patients who are undergoing rehabilitation after a stroke, reports a research update in the American Journal of Physical Medicine & Rehabilitation, the official journal of the Association of Academic Physiatrists. Noninvasive repetitive transcranial magnetic stimulation (rTMS) – especially high-frequency stimulation on the same...
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Boosting the effects of vitamin D to tackle diabetes
Enhanced activation of vitamin D curbs type 2 diabetes progression in animal models. Left: damaged insulin positive B cells (red) in a diabetic mouse pancreas. Right: B cells (red) were protected in a diabetic mouse pancreas treated with a combination of a vitamin D activator and BRD9 inhibitor. LA JOLLA–(May 10, 2018) More than 27...
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TGen develops quality-control test for detecting cancer in blood
Rapid, non-invasive diagnosis assisted by TGen assay could be used to help detect many types of cancer PHOENIX, Ariz. — May 9, 2018 — Imagine how much patients could benefit if you could discover the presence of cancer, and even how that cancer develops over time, with a simple blood test. There is vast potential...
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New biomarker identified for early diagnosis of lung cancer
CKAP4 is a potential new diagnostic marker that is detectable in patients with stage I disease and could change current practice in diagnosing lung cancer, reports The American Journal of Pathology Philadelphia, May 8, 2018 – High levels of cytoskeleton-associated protein 4 (CKAP4) have been identified in the blood of patients with lung cancer. In...
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Impaired brain pathways may cause attention problems after stroke
Stroke lesions. A, Lesion incidence map in patients with acute stroke. B, Lesion incidence map shows regions in which at least 10 patients had a lesion. Color bar denotes the probability of lesion distribution. Damage to some of the pathways that carry information throughout the brain may be responsible for attention deficit in patients who...
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Amplification of key cellular organizer may initiate cancer, study suggests
Cells begin to accumulate centrosomes—organelles that play a vital role during cell division—before they transform into cancer cells, according to a new study of patients with Barrett’s esophagus condition, which is associated with esophageal cancer. The research, which will be published May 8 in the Journal of Cell Biology, suggests that similar cases of centrosome amplification may...
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New device could mean end of the jab for people living with diabetes
Researchers from The University of Western Australia are testing the effectiveness of a device in the long-term treatment of the low blood glucose form of diabetes and are in need of community participants for the study. Low blood glucose is a potentially fatal complication of diabetes, especially for patients who are on insulin. It affects many Australians every year...
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Physicists link specific iron forms to Alzheimer’s
There have been indications for decades that there is a link between increased iron levels in the brain and Alzheimer’s disease. Leiden physicists now report a distinction between different forms of iron, identifying specific iron forms that increase in Alzheimer’s patients. The research is published in Scientific Reports. Iron plays an important role in biological processes, including those...
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Application of human induced pluripotent stem cells in precision medicine for hereditary diseases
Researchers at Li Ka Shing Faculty of Medicine of The University of Hong Kong (HKU) have successfully demonstrated the use of human induced pluripotent stem cells (hiPSCs) from patients’ skin cells for therapeutic drug testing. The success of the research implies that scientists are one step closer to applying stem cells in precision medicine in treating patients suffering...