Month: <span>May 2018</span>

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Autism may be more prevalent than previously thought

ASD Homepage Research & Tracking Autism and Developmental Disabilities Monitoring (ADDM) Network The Autism and Developmental Disabilities Monitoring (ADDM) Network is a group of programs funded by CDC to estimate the number of children with autism spectrum disorder (ASD) and other developmental disabilities living in different areas of the United States. The ADDM Network sites all...

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Publication details IDRI’s promising leprosy vaccine candidate

A publication in Nature Partner Journals (npj) Vaccines indicates that post-exposure prophylaxis with LepVax, IDRI’s leprosy vaccine candidate, not only appears safe but, unlike BCG (a tuberculosis vaccine that provides some protection against leprosy), alleviates and delays the neurologic disruptions caused by Mycobacterium lepraeinfection in nine-banded armadillos. This is an important finding because armadillos are the only other...

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UAB-led study shows drug effectiveness in reducing glucocorticoid-induced bone loss

The drug denosumab was superior to a commonly used drug in a 12-month study enrolling 795 patients UNIVERSITY OF ALABAMA AT BIRMINGHAM IMAGE: KEN SAAG BIRMINGHAM, Ala. – About one in every 100 people in the world takes glucocorticoids long term to treat immune-mediated diseases. However, glucocorticoids, such as prednisone, have a side effect — they...

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Music activates regions of the brain spared by Alzheimer’s disease

Ever get chills listening to a particularly moving piece of music? You can thank the salience network of the brain for that emotional joint. Surprisingly, this region also remains an island of remembrance that is spared from the ravages of Alzheimer’s disease. Diagram of brain networks involved in processing attention. Researchers at the University of Utah...

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The end of slings and crutches? ‘Extraordinary’ glue could soon fix broken bones in just 5 MINUTES

Swedish researchers claim it could help millions of patients with osteoporosis Experiments on rat bones showed the glue was successful at fixing fractures Further studies are needed to confirm it works in humans, the scientists said  An ‘extraordinary’ glue that could fix broken bones in a matter of minutes has been developed by scientists. Swedish researchers claim it could...

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CRISPR As Disease-Detector

Mammoth Biosciences, a company co-founded by CRISPR researcher Jennifer Doudna, has announced it is developing a platform to detect and diagnose disease using CRISPR technology, as GenomeWeb has reported. Company co-founder Trevor Martin from Stanford University tells the Verge that CRISPR isn’t just a gene-editing tool, but is “biology’s search engine.” The Verge adds that CRISPR can be...

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Largest-ever study of thyroid cancer genetics finds new mutations, suggests immunotherapy

University of Colorado Cancer Center researchers recently completed the largest-ever study of thyroid cancer genetics, mining the data of 583 patient samples of advanced differentiated thyroid cancer and 196 anaplastic thyroid cancers. In addition to the identification of specific genes that may drive these cancers and thus provide attractive targets for treatment, the researchers found that in several samples...

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Platelet-rich plasma for cosmetic facial procedures — promising results, but evidence has limitations

Most studies evaluating platelet-rich plasma (PRP) injection for facial rejuvenation and other cosmetic procedures have reported positive results, according to a critical review in the May issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).  But the research evidence supporting PRP for facial aesthetic procedures has important limitations – especially a lack...

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Protein responsible for Leukemia’s aggressiveness identified

(Boston)–Researchers have identified a protein critical for the aggressiveness of T-cell leukemia, a subtype of leukemia that afflicts children and adults.  The identification of ubiquitin-fusion degradation 1 (UFD1) allows for better understanding what causes leukemia to progress and become highly aggressive and treatment-resistant, and may lead to a new treatment for this type of cancer.  Leukemia...