Drug fights graft-versus-host-disease in mice An investigational drug in clinical trials for rheumatoid arthritis prevents a common, life-threatening side effect of stem cell transplants, new research from Washington University School of Medicine in St. Louis shows. Studying mice, the researchers found the drug prevented what’s known as graft-versus-host disease, a debilitating, sometimes lethal condition that develops when transplanted...
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Diagnostic device uses smartphone to check almost 100 samples at once
Smartphone-based diagnostic devices allow doctors in resource-poor regions to perform tests that would otherwise involve sending samples off to a distant lab. Most such devices, however, can only analyze individual samples. By contrast, a new one can check 96 samples for diseases, all at one time. Known as the mReader, the portable device was designed by...
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Research shows possible new target for immunotherapy for solid tumors
Scanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Research from the University of Cincinnati (UC) reveals a potential new target to help T cells (white blood cells) infiltrate certain solid tumors. This study, being published in the April 24 advance online edition of...
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Serlopitant found to be safe, effective for chronic pruritus
Serlopitant has potential as a therapy for the treatment of chronic pruritus, according to a study published in the May issue of the Journal of the American Academy of Dermatology. Gil Yosipovitch, M.D., from the University of Miami, and colleagues assessed the safety and efficacy of the P/neurokinin 1 receptor antagonist serlopitant in treating chronic pruritus...