Diagnostic and treatment guidelines aren’t sexy, but they play a vital role in the practice of medicine. Physician societies, government agencies, and others issue detailed recommendations for everything from who should receive cardiac stents to which antibiotics patients should get to avoid infections after knee surgery. These documents are essential for the provision of evidence-based care, as...
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Researchers pinpoint new subtype of prostate cancer
Tumors with alterations in the CDK12 gene were more responsive to immunotherapy, suggesting precision medicine approach MICHIGAN MEDICINE – UNIVERSITY OF MICHIGAN IMAGE: DEPICTION OF THE MOLECULAR PROCESSES INVOLVED IN A NEW SUBTYPE OF METASTATIC PROSTATE CANCER CHARACTERIZED BY LOSS OF THE GENE CDK12. CREDIT: ALEXANDER TOKAREV, ELLA MARU STUDIO ANN ARBOR, Michigan — Researchers led...
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MD Anderson, Houston Methodist scientists detect new ovarian cancer target
Preclinical research shows malignant cells’ tie to supportive fibroblasts can be hit with Calcitriol UNIVERSITY OF TEXAS M. D. ANDERSON CANCER CENTER Researchers at Houston Methodist Research Institute and The University of Texas MD Anderson Cancer Center have found a prescription drug, Calcitriol, approved by the Food and Drug Administration for the treatment of calcium...
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Spatial memory patterns mapped
Researchers at Cardiff University have mapped out how we store long-term spatial memory, shedding light on how our brains remember where things are within our surroundings. Professor Frank Sengpiel, from Cardiff University’s School of Biosciences, said: “Until now, how the brain stores information about our environment over long periods of time has been a mystery....
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World-first test could predict risk of heart attack in coronary artery disease patients
Researchers have developed a world-first blood test which improves the prediction of the long-term risk of heart attack or death in those with severe coronary artery disease. A new blood test could help those with severe coronary artery disease. Credit: University of Melbourne The Austin Health and University of Melbourne study published in PLOS ONE today, found...
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Errors Trigger Retraction Of Study On Mediterranean Diet’s Heart Benefits
Ask just about anybody, and you’ll probably hear that a healthy diet is one full of fruits and vegetables, olive oil, nuts and fish — what’s called Mediterranean diet. A lot of research has suggested people who eat this way tend to be healthier, but it’s been harder to prove whether that is because of the...
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Combining NSAIDs and TNFi may reduce radiographic progression in ankylosing spondylitis
June 14, 2018, European League Against Rheumatism The results of a cohort study presented at the Annual European Congress of Rheumatology (EULAR 2018) showed that, in patients with ankylosing spondylitis (AS) taking tumour necrosis factor (TNF) inhibitors, the addition of non-steroidal anti-inflammatory drugs (NSAIDs) was associated with significantly less radiographic progression in a dose-related manner at...
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Access to investigational medicines for terminally ill through expanded access programs
Bottom Line: A new study identified investigational medicines made available through expanded access programs for patients with life-threatening illnesses prior to approval from the U.S. Food and Drug Administration to assess the timing and duration of investigational drug availability. Authors: Joseph S. Ross, M.D., M.H.S., of Yale University School of Medicine, New Haven, Connecticut, and coauthors To Learn...
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EEG can determine if a depressed patient will do better on antidepressants or talk therapy
UNIVERSITY OF ILLINOIS AT CHICAGO People react differently to positive events in their lives. For some, a small reward can have a large impact on their mood, while others may get a smaller emotional boost from the same positive event. These reactions can not only be objectively measured in a simple office evaluation, but researchers...
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Clinical advances in systemic lupus erythematosus
New data on a promising biological treatment and successful use of shingles vaccine EUROPEAN LEAGUE AGAINST RHEUMATISM The results of two studies presented today at the Annual European Congress of Rheumatology (EULAR 2018) demonstrate exciting advances for individuals suffering from systemic lupus erythematosus (SLE).1,2 The first is a phase II clinical study of a promising oral treatment,...