People who develop abnormally frequent cases of a skin cancer known as basal cell carcinoma appear to be at significantly increased risk for the development of other cancers, including blood, breast, colon and prostate cancers, according to a preliminary study by researchers at the Stanford University School of Medicine. The increased susceptibility is likely caused...
Scientists identify genetic marker for gastric cancer prognosis
Although immunotherapy is seen as a very promising treatment for cancer, currently only 20 to 30 percent of patients respond positively. Being able to identify the people most likely to benefit from the costly therapy is a Holy Grail for oncologists. Histopathology of Helicobacter pylori infection in a gastric foveolar pit demonstrated in endoscopic gastric...
Treating pain with magnetic fields
Scientists have designed a hydrogel loaded with magnetic particles and laboratory-grown neurons. By applying magnetic force, the researchers were able to reduce the pain signaling of the neurons. In the United States, chronic pain is “the most common cause of long-term disability.” When applied to neurons, a magnetic field can reduce the cells’ pain signals,...
Catch-up HPV vaccine effective for women aged up to 20 years, US study suggests
US study confirms effectiveness of quadrivalent human papillomavirus (HPV) vaccine in women aged up to 20 years who receive all three doses, but more research is needed in women aged 21-26 years. Electron micrograph of a negatively stained human papilloma virus (HPV) which occurs in human warts. Credit: public domain For women aged 14-20 years, catch-up HPV...
CU researchers identify potential target for developing obesity and diabetes treatment
UNIVERSITY OF COLORADO ANSCHUTZ MEDICAL CAMPUS AURORA, Colo. (Aug. 9, 2018) – A newly published study by researchers from the University of Colorado School of Medicine has identified a potential therapeutic target for treating obesity and diabetes. The scientists studied the biological function of an epigenetic modifier known as histone deacetylase 11 (HDAC11), and determined...
Melanoma linked with CLL, close monitoring recommended
UNIVERSITY OF ROCHESTER MEDICAL CENTER While studying a large group of individuals with chronic lymphocytic leukemia (CLL), a Wilmot Cancer Institute scientific team made an important discovery — these patients had a sizable 600 percent higher risk of melanoma, the most dangerous form of skin cancer. Although a higher risk of melanoma had been known,...
New theory may explain cause of depression and improve treatments
A review of recent studies suggests mitochondria may be the root cause of depression, providing an opportunity for novel antidepressant medication A new area in depression research suggests dysfunction in mitochondria — the main source of energy for cells — could lead to major depression. Published in Frontiers in Neuroscience, this new insight to long-held theories...
Surprise finding in neurons
UNIVERSITY OF WÜRZBURG Purkinje cells are a central part of the human cerebellum, the part of the brain that plays an important role in motor learning, fine motor control of the muscle, equilibrium and posture but also influences emotions, perception, memory and language. IMAGE: IMMUNOFLUORESCENCE IMAGE FROM THE CEREBELLAR CORTEX REGION OF BIPOLAR PATIENTS THAT SHOWS...
Discovery presents treatment hope for Alzheimer’s and other neurodegenerative diseases
UNIVERSITY OF SOUTH AUSTRALIA There is new hope for the treatment of Alzheimer’s and other neurological diseases following a ground-breaking discovery made by an Australian-Chinese research collaboration. IMAGE: THIS IS A 3D ILLUSTRATION OF NERVE CELLS, CONCEPT FOR NEUROLOGICAL DISEASES, TUMORS AND BRAIN SURGERY. Researchers from the University of South Australia and the Third Military Medical University...
Tbx6 revealed as crucial to heart and skeleton formation from stem cells
Joint research with the University of Tsukuba shows Tbx6 is required for mesoderm formation and temporally controls cardiac/somite lineage diversification UNIVERSITY OF TSUKUBA Tsukuba, Japan – Many studies have attempted to identify a single transcription factor that can induce formation of mesoderm, an early layer in embryonic development, without help from other cellular proteins; none...