(HealthDay)—Tamsulosin does not significantly increase the urinary stone passage rate compared with placebo, according to a study published online June 18 in JAMA Internal Medicine. Andrew C. Meltzer, M.D., from the George Washington University School of Medicine & Health Sciences in Washington, D.C., and colleagues randomized 512 patients presenting in an emergency department with symptomatic urinary stone in...
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Researchers discover new type of lung cell, critical insights for cystic fibrosis
Researchers have identified a rare cell type in airway tissue, previously uncharacterized in the scientific literature, that appears to play a key role in the biology of cystic fibrosis. Using new technologies that enable scientists to study gene expression in thousands of individual cells, the team comprehensively analyzed the airway in mice and validated the results...
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Stem cell research for cystic fibrosis leaps forward
The fight against cystic fibrosis (CF) has taken a major step forward, with pioneering research by University of Adelaide scientists showing that cells causing the debilitating genetic disorder could be successfully replaced with healthy ones. IMAGE: GENE THERAPY TREATED AIRWAY STEM CELLS. The research published in the journal Stem Cell Research and Therapy applies cell transplantation therapy, normally used in bone marrow transplants to...
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Researchers examining Parkinson’s resilience
Diseases have a spectrum of risk, even those partially embedded in genes such as Parkinson’s disease. C. elegans, seen here as hundreds living on a plate viewed through the lens of a microscope, share roughly half their genes with humans. Credit: the University of Alabama in Tuscaloosa Less than 10 percent of those with Parkinson’s...
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SSB1: Is there a way to delay the aging process, reverse DNA damage, and prevent cancer by restoring a natural protein in the body or turning it off?
To understand what therapeutics could benefit aging and DNA damage, we have to consider what molecules are involved. So, what do we know about this process? There are a number of factors that are involved in the aging process. Many things such as diet, lifestyle, medication, genetics, diseases, amongst countless others, are involved. However, in...
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The 3 Best Peptide and Stem Cell Combinations with Great Therapeutic Potential
Current medical therapies fail to restore tissue damage due to degenerative conditions, normal aging processes, ischemia and traumatic injuries. Tissue regeneration and organ engineering have shown promise as novel treatment strategies for patients requiring tissue or whole organ replacement. Modern approaches to regenerative tissue therapies typically revolve around the use of stem cells.[i] The development of pluripotent...
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Mitochondrial Peptides: Their Effect on Aging
Published 07/25/18 Mitochondria have long been recognized as the metabolic powerhouse in the body, and their functionality is critical to a number of processes. Interestingly, in recent years their role in signaling is being consistently appreciated. Thus, identifying reading frames that encode peptides has been a crucial component of research. One peptide that has been a huge...
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New stem cell model can be used to test treatments for a rare nervous system disorder
A City of Hope researcher has developed a stem cell model to assess possible treatments for a rare nervous system disorder that is in the same disease group as Alzheimer’s disease, Parkinson’s disease and amyotrophic lateral sclerosis (ALS). An Alexander disease patient’s stem cell-derived astrocytes (green) inhibits the growth of precursor cells that become myelin...
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New anti-cancer drugs put cancers to sleep—permanently
In a world first, Melbourne scientists have discovered a new type of anti-cancer drug that can put cancer cells into a permanent sleep, without the harmful side-effects caused by conventional cancer therapies. Killer T cells surround a cancer cell. Credit: NIH Published today in the journal Nature, the research reveals the first class of anti-cancer drugs that work by putting...
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Cancer cells are weaker when made more acidic
Cancer cells function less well and are less able to multiply when their internal environment is made more acidic. Making cancer cells more acidic could quell their ability to multiply. This was the conclusion that researchers in the United States and Spain came to after they used a computer model to study the conditions that affect metabolic...