A pilot clinical trial exploring the benefit of d-amphetamine combined with physical therapy for stroke patients found no evidence that the regimen improved post-stroke motor recovery. A blood clot forming in the carotid artery. Credit: copyright American Heart Association The results, published in the Aug. 27, 2018 issue of JAMA Neurology, are “another step to...
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RFM better than BMI for measuring body fat
Body mass index, or BMI, is a widely-used value to determine if a person is underweight, normal, overweight, or obese for their height. Calculated by dividing one’s weight in kilograms by one’s height in meters squared, BMI is often criticized because it doesn’t take into account gender differences and doesn’t distinguish between bone mass, muscle...
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Overlooked molecule might be key to how well cancer-fighting CAR-T cells work
A mostly overlooked component of CAR-T cells has a surprisingly strong effect on the cancer-fighting cells’ behavior, scientists reported on Tuesday, including in ways that might affect their safety and efficacy. The component is called the co-stimulatory domain, and the two CAR-T therapies approved last year to treat forms of leukemia and lymphoma — Yescarta...
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Current advice to limit dairy intake should be reconsidered
Munich, Germany – UNDER EMBARGO UNTIL 28 Aug 2018: The consumption of dairy products has long been thought to increase the risk of death, particularly from coronary heart disease (CHD), cerebrovascular disease, and cancer, because of dairy’s relatively high levels of saturated fat. Yet evidence for any such link, especially among US adults, is inconsistent....
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Study shows AI can deliver specialty-level diagnosis in primary care setting
Results earn first FDA clearance of AI for autonomous detection of diabetic retinopathy UNIVERSITY OF IOWA HEALTH CARE A system designed by a University of Iowa ophthalmologist that uses artificial intelligence (AI) to detect diabetic retinopathy without a person interpreting the results earned Food and Drug Administration (FDA) authorization in April, following a clinical trial in primary...
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Cataplexy in narcolepsy
Contraindications XYREM is contraindicated • in combination with sedative-hypnotics or alcohol and • in patients with succinic semialdehyde dehydrogenase deficiency. This is a rare disorder of inborn error of metabolism variably characterized by mental retardation, hypotonia, and ataxia. Warnings and Precautions Central Nervous System Depression The concurrent use of XYREM with other CNS depressants, including...
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New urine dipstick test detects cause of disease that blinds millions
Scientists at Scripps Research have developed a urine diagnostic to detect the parasitic worms that cause river blindness, also called onchocerciasis, a tropical disease that afflicts 18 to 120 million people worldwide. Described in the journal ACS Infectious Diseases, the new, non-invasive test may provide an inexpensive method of determining in real time whether a...
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Nasal Spray Flu Vaccine Back On CDC Approved List
The Centers for Diseases Control and Prevention has finally added the nasal version of the influenza vaccine in time for flu season. The updated 2018-2019 advisory published by the public health agency give recommendations on which flu shots should be administered to patients. This year, the nasal spray influenza vaccine has been added, giving doctors the freedom...
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Aspirin disappoints for avoiding first heart attack, stroke
Taking a low-dose aspirin every day has long been known to cut the chances of another heart attack, stroke or other heart problem in people who already have had one, but the risks don’t outweigh the benefits for most other folks, major new research finds. This Thursday, Aug. 23, 2018 photo shows an arrangement of...
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Four out of 10 patients with atrial fibrillation have unknown brain damage
Munich, Germany – Aug. 26, 2018: Four out of ten patients with atrial fibrillation but no history of stroke or transient ischaemic attack have previously unknown brain damage, according to the first results of the Swiss Atrial Fibrillation Cohort Study (Swiss-AF) presented today at ESC Congress 2018.1 “Our results suggest that clinically unrecognized brain damage...