Munich, Germany – 28 Aug 2018: Combined oral anticoagulant and antiplatelet therapy is associated with a worse prognosis than anticoagulation alone in newly diagnosed atrial fibrillation patients without a clear indication for antiplatelets, according to late breaking results from the GARFIELD-AF registry presented today at ESC Congress 2018.1 Professor Keith Fox, principal investigator, University of...
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Researchers develop ‘cytological ruler’ to build 3D map of human genome
It has been almost 20 years since the human genome was first sequenced, but researchers still know little about how the genome is folded up and organized within cells. In a paper to be published August 28 in the Journal of Cell Biology, researchers from the University of Illinois at Urbana-Champaign describe a new technique...
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Combination approach shows promise for beating advanced melanoma
In UCLA-led study, new treatment is more effective in people receiving immunotherapy for the first time UNIVERSITY OF CALIFORNIA – LOS ANGELES HEALTH SCIENCES A UCLA-led study has found that a treatment that uses a bacteria-like agent in combination with an immunotherapy drug could help some people with advanced melanoma, an aggressive form of skin...
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Treating inflammatory bowel disorder by delivering microRNAs
Osaka University researchers deliver microRNAs to suppress inflammatory reaction to affected areas in patients with inflammatory bowel disorder OSAKA UNIVERSITY Inflammatory bowel disease (IBD), such as Crohn disease and ulcerative colitis, are chronic inflammatory diseases of unknown cause, and the number of IBD patients is on the rise. IMAGE: MIR-29 LOADED ON A SUPERCARBONATE APATITE PREVENTS THE DEVELOPMENT...
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Diseased heart muscle cells have abnormally shortened telomeres, researchers find
People with a form of heart disease called cardiomyopathy have abnormally short telomeres in heart muscle cells responsible for contraction, according to a new study by researchers at the Stanford University School of Medicine. Human chromosomes (grey) capped by telomeres (white). Credit: PD-NASA; PD-USGOV-NASA A telomere is a DNA sequence that serves as a protective cap on the ends...
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Analysis: Commonly used drugs are rarely studied in primary care patients
Drugs most commonly prescribed to patients seen by primary care physicians are not often tested in the patients who go to these clinics, where most people receive their care, say investigators at Georgetown University Medical Center (GUMC) and Yale School of Medicine. The study, published in the September edition of Journal of General Internal Medicine, looked...
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The natural sugar that reduces the risk of diabetes in mice
Sugar may be the villain of our time, with too much of the sweet stuff known to be a leading cause of developing diabetes. But now researchers at Washington University School of Medicine in St. Louis have discovered a new way to reduce the risk of this condition – sugar. Trehalose is a natural sugar that has...
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INRS takes aim at dreaded tropical disease leishmaniasis
Leishmania is a microorganism that enters the human body via a sandfly bite. The parasite allows itself to be swallowed up by white blood cells to advance its life cycle. The disease threatens the health of over 500 million people at risk of infection in Africa, Europe, Asia and the Americas. Credit: CC0 Public Domain...
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MS researchers find new ways to regenerate the brain’s insulation
University of Melbourne researchers have found a way to rebuild damaged nerve coverings that cause Multiple Sclerosis. Myelin sheath. Credit: Wikipedia Finding ways to restore the myelin sheath is recognised as important to preventing the progression of disability in MS patients. Researcher Jessica Fletcher led the team who made the discovery and their findings are published in...
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How does manganese enter the brain? Research offers clues to neurological disorder
New information from the University at Buffalo on how manganese, an essential nutrient, gets into the brain, is helping shed light on a neurological disorder usually associated with industrial overexposure to the metal. In June, Brittany Steimle, a doctoral candidate in biochemistry at UB, received the award for outstanding poster for her presentation on how...