We know that our bodies learn how to mount efficient defenses to disease and infection after exposure to such health hazards. In short, our bodies “learn” to identify the culprits and how to destroy them. Where is that “memory” activated and the response mounted? New research finally reveals where the immune response actually starts in the body....
Post
Researchers work on scientific foundation for new forms of therapy in neurodegenerative processes
Protective proteins that mitigate the destruction of nerve cells after a stroke can be administered into the brain through the nose, as Heidelberg University researchers demonstrated using a mouse model. The team led by Prof. Dr. Hilmar Bading at the Interdisciplinary Center for Neurosciences (IZN) is laying the scientific groundwork for new forms of therapy...
Post
Researchers stop cell suicide that worsens sepsis, arthritis
Researchers from Case Western Reserve University School of Medicine have discovered a way to stop immune cell death associated with multiple diseases, including sepsis, inflammatory bowel disease (IBD), and arthritis. Credit: CC0 Public Domain The findings, published in Science Immunology, identify a chemical that potently inhibits inflammatory cell death. Cells often perforate their own membranes in...
Post
APOBEC-Linked Mutational Signatures Drive Skin Cancer in Recessive Dystrophic Epidermolysis Bullosa
NEW YORK (GenomeWeb) – Mutational signatures linked to the APOBEC family drive the development of early-onset squamous cell carcinomas of the skin among individuals with a rare genetic disorder condition. Recessive dystrophic epidermolysis bullosa (RDEB) is a rare genetic disorder caused by COL7A1 mutations that lead to skin fragility, tissue damage, and inflammation. Wounds that...
Post
Tai Chi Beats Aerobic Exercise for Fibromyalgia
Compared with aerobic exercise, the traditional martial art of tai chi is as good as, or better than, aerobic exercise, for improving the overall severity of fibromyalgia symptoms, new research shows. Results of a 52-week single-blind trial showed that in addition to fibromyalgia symptom relief, tai chi was associated greater improvements in depression, anxiety, self-efficacy,...
Post
The molecular changes caused by sleep loss, and how that leads to weight gain
A great number of observational studies have suggested that sleep loss or disrupted circadian rhythms due to shift work are associated with obesity, type 2 diabetes and a variety of other dysfunctional metabolic conditions. A study from Uppsala University is now offering evidence that helps better explain how tissue-level molecular changes are brought on by...
Post
Sleeping 5 hours or less a night associated with doubled risk of cardiovascular disease
EUROPEAN SOCIETY OF CARDIOLOGY Munich, Germany – Aug. 26, 2018: Middle-aged men who sleep five hours or less per night have twice the risk of developing a major cardiovascular event during the following two decades than men who sleep seven to eight hours, according to research presented today at ESC Congress 2018.1 Study author Ms...
Post
The health benefits of eating earlier
(HealthDay)—Weight loss depends on eating fewer calories than your body uses up. But when you eat those calories could make a difference that you’ll see on the scale. An Italian study found that you can boost weight loss by about 25 percent just by eating 70 percent of each day’s calories between breakfast and lunch, including a mid-morning snack,...
Post
Low carbohydrate diets are unsafe and should be avoided
EUROPEAN SOCIETY OF CARDIOLOGY Munich, Germany – Aug. 28, 2018: Low carbohydrate diets are unsafe and should be avoided, according to a large study presented today at ESC Congress 2018.1 IMAGE: THIS IS A FIGURE. Study author Professor Maciej Banach, of the Medical University of Lodz, Poland, said: “We found that people who consumed a low...
Post
Take a vacation — it could prolong your life
EUROPEAN SOCIETY OF CARDIOLOGY Munich, Germany – 28 Aug 2018: Taking vacations could prolong life. That’s the finding of a 40-year study presented today at ESC Congress and accepted for publication in The Journal of Nutrition, Health & Aging.1,2 IMAGE: FIGURE OF THE INTERVENTION AND CONTROL GROUPS. “Don’t think having an otherwise healthy lifestyle will compensate for...