Year: <span>2018</span>

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How an existing diabetes drug controls pancreatic cancer

New research suggests that targeting a particular cell signaling pathway with the diabetes drug metformin might offer a way to stop the progression and spread of pancreatic cancer. The study — which was led by Rutgers Cancer Institute of New Jersey in New Brunswick — is to feature at the 2018 annual meeting of the American...

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Peptide Hydrogel Promotes Tissue Growth to Heal Without Drugs

Rice University researchers studying how different drugs, proteins, and cells embedded in peptide hydrogel can boost healing and promote tissue formation, discovered that the hydrogel itself exhibits powerful therapeutic properties. Their self-assembling multidomain peptide (MDP) with the amino acid sequence K2(SL)6K2 can be injected into tissue to provide a place for new cells to grow, the...

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Compound scores key win in battle against antibiotic resistance

Researchers at Oregon State University have made a key advance in the fight against drug resistance, crafting a compound that genetically neutralizes a widespread bacterial pathogen’s ability to thwart antibiotics. The findings are important because antibiotic resistance is a growing global threat, with the percentage of isolates with multidrug resistance on the rise for many...

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For nanomedicine, cell sex matters

Important biological differences between men and women exist – right down to the cellular level. Investigators from Brigham and Women’s Hospital and colleagues at Stanford University, McGill University and University of California, Berkeley wanted to determine if differences between male versus female cells may influence how well cells uptake nanoparticles – a key vehicle for...

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Physically fit women nearly 90 percent less likely to develop dementia

Women with high physical fitness at middle age were nearly 90 percent less likely to develop dementia decades later, compared to women who were moderately fit, according to a study published the March 14, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study measured the women’s cardiovascular fitness...