Patients with high blood pressure and progression of periventricular white matter hyper intensities showed signs of cognitive impairment despite taking medication to lower their blood pressure, according to new research in the American Heart Association’s journal Hypertension. High blood pressure has been linked to an increased risk for dementia, but what’s unclear is what kinds...
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Statin therapy reduces risk for diabetic retinopathy in T2DM
(HealthDay)—For Taiwanese patients with type 2 diabetes and dyslipidemia, statin therapy is associated with a reduced risk for diabetic retinopathy, according to a study published online Jan. 10 in JAMA Ophthalmology. Eugene Yu-Chuan Kang, M.D., from the Chang Gung Memorial Hospital in Taoyuan, Taiwan, and colleagues examined the correlation between statin therapy and development of...
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Researchers identify experimental Immunotherapy approach to target acute myeloid leukemia
University of North Carolina Lineberger Comprehensive Cancer Center researchers have identified a potential way to target a subtype of acute myeloid leukemia (AML) using chimeric antigen receptor (CAR) T-cell therapy, a form of immunotherapy in which patients’ immune cells are genetically engineered to recognize and track their cancer. Credit: CC0 Public Domain At the 60th...
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Metabolite from pomegranate diet reduces inflammatory bowel diseases
inStem and University of Louisville research teams identify Urolithin A and its synthetic analog to improve gut barrier and reduce inflammation NATIONAL CENTRE FOR BIOLOGICAL SCIENCES Bangalore, INDIA – Millions of people suffer from inflammatory bowel disease (IBD) worldwide, either in the form of ulcerative colitis or Crohn’s disease, and few effective long-term treatments are...
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Genomic analysis is important even for ultra-hypermutated tumors prior to immune therapy
New research from The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC-James) underscores the importance of genomic analysis of rare malignant tumors that are genetically unstable and have high numbers of gene mutations. Killer T cells surround a cancer cell. Credit: NIH OSUCCC-James investigators analyzed the cancer genomes of nine metastatic tumors and the...
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Does PTSD affect heart disease and cancer risk?
Posttraumatic stress disorder (PTSD) was associated with cardiovascular disease and cancer, as well as the metabolic syndrome, in a new study. Regions of the brain associated with stress and post traumatic stress disorder. Credit: National Institutes of Health In the Journal of Neuroscience Research study of 84 individuals diagnosed with PTSD (39 victims of terrorist...
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Researchers overcome hurdle in CRISPR gene editing for muscular dystrophy
The gene editing technique known as CRISPR is a revolutionary approach to treating inherited diseases. However, the tool has yet to be used to effectively treat long-term, chronic conditions. A research team led by Dongsheng Duan, Ph.D., at the University of Missouri School of Medicine has identified and overcome a barrier in CRISPR gene editing...
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Technique boosts omega 3 fatty acid levels in brain
Getting enough of the omega 3 fatty acids DHA and EPA into the brain to study their effects on conditions such as Alzheimer’s and depression—which they have been shown to help—is no easy task. While supplements containing these fatty acids exist, there is scant evidence showing that these supplements actually increase DHA or EPA in the brain. To measurably increase levels of EPA in the brain, a...
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Brain plasticity restored in adult mice through targeting specific nerve cell connections
Research in mice led by neuroscientists at Tufts University School of Medicine reveals a new molecular mechanism that is essential for brain maturation and may be used to restore plasticity in aged brains. The study focused on a subtype of inhibitory cell also found in people called Parvalbumin neurons (stained in blue) which exert significant...
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Eye Color May Be Linked To Seasonal Depression, Says Study
People suffering from winter Seasonal Affective Disorder may experience low mood, increased sleepiness, social withdrawal, and a craving for high starch foods. The study published in the Open Access Journal of Behavioural Science & Psychologygave questionnaires to a sample size of 175 student participants to understand the extent of mood variations due to changing seasons....