New cell atlas reveals immune cells present in zones of human kidney WELLCOME TRUST SANGER INSTITUTE The first cell atlas of the human kidney’s immune system has been created after scientists mapped nearly 70,000 individual kidney cells from early life and adults. Researchers at the Wellcome Sanger Institute, University of Cambridge, Newcastle University and their...
Post
First melanoma test identifies those at low risk of cancer spreading
by Newcastle University ITV Tyne Tees presenter, Pam Royle, is one of the first to try a new test developed by Newcastle University which predicts whether her skin cancer is likely to return. The test which reliably predicts that a melanoma is unlikely to spread or return has been developed by scientists at Newcastle University....
Post
Immunologists identify T cell homing beacons for lungs
by Quinn Eastman, Emory University Scientists have identified a pair of molecules critical for T cells, part of the immune system, to travel to and populate the lungs. A potential application could be strengthening vaccines against respiratory pathogens such as influenza. The findings were published online Thursday, September 26 in Journal of Experimental Medicine. Much...
Post
To Pay Attention, the Brain Uses Filters, Not a Spotlight
A brain circuit that suppresses distracting sensory information holds important clues about attention and other cognitive processes. We can pick out a conversation in a loud room, amid the rise and fall of other voices or the hum of an air conditioner. We can spot a set of keys in a sea of clutter, or...
Post
Serum IL-35 levels tied to bone loss with rheumatoid arthritis
Yuxuan Li, from the First Affiliated Hospital of China Medical University in Shenyang, and colleagues explored the correlations between IL-35 levels and bone loss in postmenopausal women, including 76 with RA and 53 healthy controls. Additionally, dual-energy X-ray absorptiometry was used to measure bone mineral density (BMD) at lumbar spine 1 to 4 and at...
Post
Inflammation amps up neurite growth, gene expression involved in heat, cold sensitivity
by Tracey Peake, North Carolina State University Researchers from North Carolina State University have found that inflammation increases neuronal activity, gene expression and sensory nerve (neurite) outgrowth in neurons involved in thermal—but not physical- sensations in mice. The work sheds light on the role that inflammation-induced over expression of calcium channel genes may play in...
Post
Anxiety disorders linked to disturbances in the cells’ powerhouses
by Public Library of Science The powerhouse of the cell, the mitochondria, provides energy for cellular functions. But those activities can become disturbed when chronic stress leads to anxiety symptoms in mice and humans. Iiris Hovatta of the University of Helsinki and colleagues report these findings in a new study published 26th September in PLOS...
Post
Genetic markers linked to the start of symptoms of Parkinson’s disease
by University of Barcelona Researchers from the Institute of Neurosciences of the University of Barcelona (UBNeuro), Hospital Clínic and the IDIBAPS have identified a group of genetic variants related to the starting point of Parkinson’s disease Credit: University of Barcelona – UBNeuro Researchers from the Institute of Neurosciences of the University of Barcelona (UBNeuro), Hospital...
Post
Light Activated Compound Kills Hypoxic Tumors
SEPTEMBER 27TH, 2019 MEDGADGET EDITORS MEDICINE, NANOMEDICINE, ONCOLOGY Photodynamic therapy is a technique that relies on photosensitizer chemicals to generate reactive species that kill cancer cells. These compounds can be delivered into tumors and then light is used to activate them. One of the main reasons for the slow adoption of this technology is that...