Research suggests that celiac disease could be caused by a bacterial enzyme used to manufacture sausages, cheese, bread and other processed foods. FRONTIERS Myths about gluten are hard to bust. Intolerance, allergy, sensitivity, hypersensitivity. What is what? Celiac disease is none of these things. It is an autoimmune disorder, where gluten triggers the immune system to attack the gut. It is common, lifelong,...
Year: <span>2019</span>
Egg metabolites in blood related to lower risk of type 2 diabetes
Consumption of one egg every day seems to associate with a blood metabolite profile that is related to a lower risk of type 2 diabetes, a new study conducted in the University of Eastern Finland shows. The findings were published in Molecular Nutrition and Food Research. Eggs remain one of the most controversial food items. High intake of eggs has traditionally been discouraged, mainly due to their...
New insight into the process of generation of new neurons in the adult brain
Researchers at Sahlgrenska Academy at the University of Gothenburg, Sweden, in collaboration with research groups in Finland, Canada, and Slovenia, have discovered a novel and unexpected function of nestin, the best known marker of neural stem cells. IMAGE: THE PICTURE SHOWS ASTROCYTES IN RED AND GREEN, THE AREAS WHERE INDIVIDUAL ASTROCYTES INTERCONNECT ARE YELLOW. A SINGLE...
Gut immune cells cut inflammation in multiple sclerosis
Researchers at the University of Toronto and UC San Francisco have discovered that the intestine is the source of immune cells that reduce brain inflammation in people with multiple sclerosis (MS), and that increasing the number of these cells blocks inflammation entirely in a preclinical model of the disease. The cells in question are plasma...
Experimental treatment shows promise against triple-negative breast cancer
Mouse study illustrates the potential efficacy of Tinagl1 protein PRINCETON UNIVERSITY By simultaneously tackling two mechanisms for cancer’s growth, an experimental therapy reduced the spread of triple-negative breast cancer in a study conducted in mice. IMAGE: TREATMENT WITH RECOMBINANT TINAGL1 PROTEIN SIGNIFICANTLY SUPPRESSED LUNG METASTASIS, AS SHOWN BY THE BLUE ARROWS IN MICE WITH (RIGHT) OR WITHOUT...
Study sheds light on the function of a long-mysterious PCSK9 mutation
Results build on developing model of new druggable PCSK9 interactor AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY High levels of low-density lipoproteins, parcels of lipids and protein that carry cholesterol, are a leading risk factor for heart disease. Many cholesterol medications lower LDL, some of them by targeting the protein PCSK9. In the January issue of the...
Controlling neurons with light — but without wires or batteries
University of Arizona research reveals a more sophisticated method for delivering light to control neurons in the brain — which could ultimately mean turning off pain receptors or reducing the effects of severe neurological disorders UNIVERSITY OF ARIZONA COLLEGE OF ENGINEERING IMAGE: WIRELESS AND BATTERY-FREE IMPLANT WITH ADVANCED CONTROL OVER TARGETED NEURON GROUPS. CREDIT: PHILIPP GUTRUF University of Arizona biomedical engineering...
A new glucose monitor for diabetics proves virtually painless and even more accurate
A more comfortable and reliable blood-sugar monitoring system is being designed by researchers in Sweden for people with diabetes. After successfully testing a prototype of a microneedle patch on a human subject, the completion of a system for clinical tests is now underway. Continuous monitoring is a way to safely and reliably lower blood glucose – giving the user...
New compound shows promise in treatment of Alzheimer’s
Yale researchers have identified a drinkable cocktail of designer molecules that interfere with a crucial first step of Alzheimer’s and even restores memories in mice, they report Jan. 2 in the journal Cell Reports. The binding of amyloid beta peptides to prion proteins triggers a cascade of devasting events in the progression of Alzheimer’s—accumulation of...
Clinical trial launches to develop breath test for multiple cancers
Researchers have launched a clinical trial to develop a breath test, analysing molecules that could indicate the presence of cancer at an early stage. This is the first test of its kind to investigate multiple cancer types. A cancer breath test has huge potential to provide a non-invasive look into what’s happening in the body and could help to find cancer early when treatment is more likely to be...