New treatment for heart attack scar UNIVERSITY OF SYDNEY Heart disease remains the largest killer in Australia and around the world. A new study has shown that a protein therapy- recombinant human platelet-derived growth factor-AB (rhPDGF-AB) – could improve outcomes following heart attack. After a heart attack, scar tissue forms and this negatively affects heart...
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Novel dementia vaccine on track for human trials within two years
By Rich Haridy A newly published study has described the successful results in mice of a novel vaccine designed to prevent neurodegeneration associated with Alzheimer’s disease. The researchers suggest this “dementia vaccine” is now ready for human trials, and if successful could become the “breakthrough of the next decade.” The new study, led by the...
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AI beats human breast cancer diagnosis
by Patrick Galey A computer programme can identify breast cancer from routine scans with greater accuracy than human experts, researchers said in what they hoped could prove a breakthrough in the fight against the global killer. Breast cancer is one of the most common cancers in women, with more than two million new diagnoses last...
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Study shows link between atopic dermatitis and vitiligo
(HealthDay)—Atopic dermatitis (AD) is associated with vitiligo, according to a review and meta-analysis published online Dec. 24 in the Journal of Cosmetic Dermatology. Prakash Acharya, M.B.B.S., M.D., and Mahesh Mathur, M.D., from the College of Medical Sciences in Bharatpur, India, conducted a meta-analysis of observational studies to compare the prevalence and risk of vitiligo in...
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Some learning is a whole-brain affair, study shows
JOHNS HOPKINS MEDICINE Researchers at Johns Hopkins Medicine have successfully used a laser-assisted imaging tool to “see” what happens in brain cells of mice learning to reach out and grab a pellet of food. Their experiments, they say, add to evidence that such motor-based learning can occur in multiple areas of the brain, even ones...
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Arterial Sca1+ Vascular Stem Cells Generate De Novo Smooth Muscle for Artery Repair and Regeneration
Highlights • Sca1 + vascular stem cells produce new smooth muscle cells after severe vessel injury • A Sca1 +PDGFRa + subpopulation contributes to vascular repair and regeneration • Sca1-derived smooth muscle cells expand more than pre-existing smooth muscle • YAP is required for Sca1-derived smooth muscle cell expansion during vascular repair Summary Rapid regeneration...
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HIV patients lose smallpox immunity despite childhood vaccine, AIDS drugs
HIV-associated immune amnesia could explain why HIV-positive people still have shorter lives than HIV-negative counterparts OREGON HEALTH & SCIENCE UNIVERSITY HIV patients lose immunity to smallpox even though they were vaccinated against the disease as children and have had much of their immune system restored with antiretroviral therapy, according to a study published in the...
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A prospective, multicentric study indicates a new feature of cluster headache attacks
by International Headache Society A prospective study recently published in the journal Cephalalgia, the official journal of the International Headache Society, extends the idea behind cluster headache chronicity. The study, entitled “Temporal changes of circadian rhythmicity in cluster headache”, was first-authored by Dr. Mi Ji Lee, from the Department of Neurology, Neuroscience Center, Samsung Medical...
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Half the amount of chemo prevents testicular cancer from coming back, new trial shows
by Institute of Cancer Research Testicular cancer can be prevented from coming back using half the amount of chemotherapy that is currently used, a new clinical trial has shown. In many men who have had surgery for an aggressive form of testicular cancer, the disease can come back elsewhere in their bodies and need intensive...
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Scientists find a new use for already known anti-cancer drugs
Researchers from Nizhny Novgorod and Ghent have proposed new approaches to enhancing the efficacy of cancer therapy and preventing the development of new tumors in the body LOBACHEVSKY UNIVERSITY The world scientific community is waging a difficult and prolonged war on cancer. New research in the field of immunogenic cell death can extend the area...