by Torsten Arndt, Fraunhofer-Gesellschaft An unpleasant tingling in the hands and feet, numbness, fuzzy and burning sensations—these symptoms may indicate a neuropathy, a disease of the nervous system. If the pain persists for several months, it is referred to as chronic pain. By then, it is very difficult to treat, and the available drugs often...
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A new breakthrough in developing effective antimalarial drugs
by Pasteur Institute Parasites in the genus Plasmodium, which cause malaria, are transmitted to humans through bites from infected mosquitoes. The parasites acclimatize to these two completely different hosts because the plasticity of their genome enables them to adapt as necessary. Scientists at the Institut Pasteur and the CNRS have investigated the epigenetic mechanisms behind...
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Mediterranean diet may help preserve the kidney health of transplant recipients
by American Society of Nephrology A new study indicates that following the Mediterranean diet may help kidney transplant recipients maintain transplant kidney function. The findings appear in an upcoming issue of CJASN. Despite improvements in the survival of transplanted kidneys in the early years after transplantation, loss of kidney function within 10 years still occurs...
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Closer to identifying leukemic stem cells
Acute myeloid leukaemia is the most common type of leukaemia in adults. It is characterized by the pathological expansion of immature cells (myeloblasts) that invade the bone marrow and expand into the blood, affecting the production of the rest of the healthy cells. Although patients usually respond well to chemotherapy-based treatments, a large proportion of...
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Heart attack: New protein therapy may improve recovery
New preclinical research in animal models finds that infusing a specific protein into scar tissue after a heart attack improves and speeds up the recovery of the heart. Researchers are soon to test a new therapy for improving heart function and recovery after a heart attack. According to the American Heart Association (AHA), around 605,000...
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Study reveals what causes type 2 diabetes and how to reverse it
As the incidence of diabetes continues to increase globally, the fight against this chronic condition continues. New research explains not only what triggers type 2 diabetes but also how to reverse the condition. The findings also shed light on what leads to remission after reversal for some people. New research looks at the causes of...
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Using gene therapy to treat chronic traumatic encephalopathy
MARY ANN LIEBERT, INC./GENETIC ENGINEERING NEWS New Rochelle, NY, January 3, 2020–A new study shows the feasibility of using gene therapy to treat the progressive neurodegenerative disorder chronic traumatic encephalopathy (CTE). The study, which demonstrated the effectiveness of direct delivery of gene therapy into the brain of a mouse model of CTE, is published in...
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Radical treatment of chronic oral infection before stem cell transplantation not necessary
UNIVERSITY OF HELSINKI A recently published study indicates that oral infections seem to have no association with the risk of stem cell transplantation patients dying of or getting a serious infection within six months of the procedure. A study collaboratively conducted by the University of Helsinki, the Helsinki University Hospital, the University of Basel and...
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Research identifies changes in neural circuits underlying self-control during adolescence
Penn study shows developing brain networks support cognition in youth UNIVERSITY OF PENNSYLVANIA SCHOOL OF MEDICINE PHILADELPHIA — The human brain is organized into circuits that develop from childhood through adulthood to support executive function–critical behaviors like self-control, decision making, and complex thought. These circuits are anchored by white matter pathways which coordinate the brain...
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Air pollution can worsen bone health
BARCELONA INSTITUTE FOR GLOBAL HEALTH (ISGLOBAL) Some of the effects of air pollution on health are well documented -lung cancer, stroke, respiratory diseases, and a long etcetera- but for others there is less scientific evidence. Such is the case of bone health: there are only a few studies and results are inconclusive. Now, a study...