Stress-related conditions such as adjustment disorder and clinical burnout can be effectively treated with a 12-week cognitive-behavioral programme, both when delivered as a face-to-face treatment and when delivered via the internet, according to a new doctoral thesis from Karolinska Institutet. Stress-related ill-health is a widespread problem around the world. Prolonged exposure to stress without sufficient...
FEBRUARY 10TH, 2020 POSTED BY ELLEN GOLDBAUM-BUFFALO Newly discovered molecules can modulate circadian rhythms by binding to a melatonin receptor in the biological clock, according to new research in mice. Like breathing or blinking, most people don’t notice the behaviors our circadian rhythms regulate, such as digestion and sleep-wake cycles. But when circadian rhythms malfunction,...
Mitochondria are known as the “powerhouses” of cells. However, under critical pathophysiological conditions, they can use cellular energy for self-preservation. This occurs when the operating mode of a molecular machine in the mitochondrial sheath becomes reversed. An international research group led by MedUni Vienna’s Center for Physiology and Pharmacology has now identified L-type calcium channels...
by John Hewitt , Medical Xpress Although most neurotransmitters perform the same basic role, they are not fungible. Each takes the baton from an incoming action potential and passes the neural message across the synaptic divide, yet each flavor of transmitter adds its own unique twist. Simply put, they have completely different metabolic actions. Properly...
By Nick Lavars Pancreatic cancer is the deadliest form of cancer with a five-year survival rate of just five percent, well behind that of many common cancer types. Scientists working to improve the odds have made an exciting breakthrough, finding that a peptide taken from the foot-and-mouth-disease virus naturally zeroes in on the majority of...
While pain relievers and hormonal drugs are the first line of treatment for endometriosis, these options have many side effects. Some people choose to try herbs as a complementary therapy. Endometriosis is a chronic medical condition that causes tissue similar to the uterine lining to grow outside of the uterus. Known as endometrial implants, they...
by CU Anschutz Medical Campus A major multi-center investigation of children with cystic fibrosis has identified a test that allows earlier identification of those at risk for cystic fibrosis liver disease. The study, which includes 11 clinical sites in North America, was led by Michael Narkewicz, MD, professor of pediatrics from the University of Colorado...
by The Mount Sinai Hospital Researchers at the Icahn School of Medicine at Mount Sinai have discovered a novel combination of two classes of drugs that, together, cause the highest rate of proliferation ever observed in adult human beta cells—the cells in the pancreas that produce insulin—without harming most other cells in the body. The...
by Columbia University School of Engineering and Applied Science Researchers at Columbia Engineering have engineered probiotics to safely deliver immunotherapies within tumors. These include nanobodies against two proven therapeutic targets—PD-L1 and CTLA-4. The drugs are continuously released by bacteria and continue to attack the tumor after just one dose, facilitating an immune response that ultimately...
by The North American Menopause Society Skeletal muscle mass and strength are critical in helping prevent falls, fractures, and disability. Yet, they continue to decline during the menopause transition. A new study showed that the prolonged use (defined as ≥13 mo) of hormone therapy (HT) was associated with higher muscle mass and less chance of...
