Month: <span>February 2020</span>

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Bioinspired microneedle patch has more sticking power
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Bioinspired microneedle patch has more sticking power

By Ben Coxworth In nature, pest insects and other parasites latch onto their hosts by inserting backward-facing barbs into their tissue. Scientists have now copied that strategy, in a system that could someday replace painful hypodermic needles. Developed at New Jersey’s Rutgers University, the new technology is a form of microneedle patch. Such patches generally...

Cancer mutations occur decades before diagnosis
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Cancer mutations occur decades before diagnosis

EUROPEAN MOLECULAR BIOLOGY LABORATORY Researchers at EMBL’s European Bioinformatics Institute (EMBL-EBI) and the Francis Crick Institute have analysed the whole genomes of over 2600 tumours from 38 different cancer types to determine the chronology of genomic changes during cancer development. Cancer occurs as part of a lifelong process in which our genome changes over time....

First comprehensive survey of virus DNA found within cancer cells
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First comprehensive survey of virus DNA found within cancer cells

UNIVERSITY OF EAST ANGLIA Researchers from the University of East Anglia have helped to carry out the first comprehensive survey of viruses found within different types of cancer. An international team systematically investigated the DNA found within more than 2,600 tumour samples from patients with 38 different types of cancer. They discovered traces of viruses...

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Protein could offer therapeutic target for breast cancer metastasis

UNIVERSITY OF KENTUCKY LEXINGTON, Ky. (Feb. 5, 2020) – A new study by University of Kentucky Markey Cancer Center researchers suggests that targeting a protein known as heat shock protein 47 (Hsp47) could be key for suppressing breast cancer metastasis. Metastasis is when cancer cells spread from the primary tumor to surrounding tissues and distant...

Parkinson’s and the immune system
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Parkinson’s and the immune system

Medicine RUHR-UNIVERSITY BOCHUM The team was thus able to provide further evidence that there are interfaces between the nervous system and immune system. The researchers hope that the protagonists or antagonists of this signalling pathway may be suitable for therapeutic interventions. They report on this in the cover story in the journal Science Signalingon 4...

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Unprecedented exploration generates most comprehensive map of cancer genomes to date

An international team has completed the most comprehensive study of whole cancer genomes to date, significantly improving our fundamental understanding of cancer and signposting new directions for its diagnosis and treatment. UNIVERSITY OF MELBOURNE An international team has completed the most comprehensive study of whole cancer genomes to date, significantly improving our fundamental understanding of...

Massive genome study unlocks secrets of how cancers form
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Massive genome study unlocks secrets of how cancers form

by Sara Hussein A massive, decade-long study sequencing the genomes of dozens of cancers has revealed the secrets of how tumours form and may pave the way for better and more targeted treatment. The Pan-Cancer Project brought together over 1,300 researchers globally to tackle the mammoth task of sequencing the genomes of 38 types of...

Team finds that their cancer-fighting compound fights obesity and diabetes, too
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Team finds that their cancer-fighting compound fights obesity and diabetes, too

by University of New Mexico Eric Prossnitz, Ph.D., and his team hope to help 93 million obese Americans fight their fat. In a paper published in Science Translational Medicine, they reported that G-1, a cancer-fighting compound they discovered some years ago, reduces fat in obese mice. Although G-1 is currently in phase 1 clinical trials...

Platelet microparticles give antibody drug ‘piggyback ride’ to repair damaged heart
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Platelet microparticles give antibody drug ‘piggyback ride’ to repair damaged heart

by North Carolina State University New research from North Carolina State University shows that platelet microparticles are an effective way to deliver therapeutic drugs directly to the heart following a heart attack. This method increases drug concentration at the site and could help heart attack patients reduce side effects from drugs used to aid recovery....