3D Cell Culture Although not a new trend, 3D culture is a growing concept in 2020. During 2019, 72,000 papers were published discussing 3D culture, in comparison to 46,000 papers in 2018. While the concept of 3D culture is not new, interesting developments and approaches are evolving. Notorious for its high failure rate, drug development...
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Research shows the way to more efficient EPO production
TECHNICAL UNIVERSITY OF DENMARK To many people, EPO rhymes with doping and cycling. But in fact, EPO is an important medical drug. This hormone works naturally in the body by stimulating red blood cell production. Patients suffering from anemia caused by for instance chronic kidney disease, AIDS or hematologic disorders can benefit immensely from EPO...
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Claws of health? Lobster blood could play role in new drugs
PORTLAND, Maine — Maine lobsters have long delighted tourists as the state’s most beloved seafood. But one company thinks the crustaceans can save human lives by providing their blood for use in new drugs. The effort, involving a longtime lobster scientist, wouldn’t be the first example of coastal invertebrates being used to aid human health....
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New insights into the processes that cause Parkinson’s disease
by Ecole Polytechnique Federale de Lausanne In a breakthrough for Parkinson’s disease, scientists at EPFL have reconstructed the process by which Lewy bodies form in the brain of patients. The study offers new insights into how Parkinson’s disease begins and evolves, and opens up a set of potential new treatment targets. The brains of patients...
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New research takes p*** out of incontinence
by University of Portsmouth Millions of people might eventually be spared the embarrassment and extreme isolation caused by wetting themselves, thanks to new research. One in every five people has a lower urinary tract disorder called overactive bladder which, for some, means not being able to hold in urine, needing to go to the toilet...
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Modified tuberculosis vaccine as a therapy for bladder cancer
by Markus Berninger, Max Planck Society The human immune system can recognize and eliminate not only germs but also cancer cells. This is why treatments with weakened germs can help the immune system in its fight against cancer. Researchers at the Max Planck Institute for Infection Biology in Berlin have genetically modified the tuberculosis vaccine...
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New study indicates amino acid may be useful in treating ALS
by Brain Chemistry Labs A naturally occurring amino acid is gaining increased attention from scientists as a possible treatment for ALS following a new study published today in the Journal of Neuropathology & Experimental Neurology. The study showed that the amino acid, L-serine, successfully reduced ALS-like changes in an animal model of ALS. The scientists...
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Researchers say extended antidepressant use creates physical dependence
by American Osteopathic Association Researchers provide a schedule for gradually reducing dosage for each class and type of antidepressant, along with associated withdrawal symptoms for which patients and physicians should monitor. Credit: JAOA Patients who have taken antidepressants for years should consider coming off the medication. However, researchers say they will likely face difficult and...
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New treatments for diabetes may lie in metabolic products of intestinal flora
by Cynthia Lee, McGill University In a study published in the journal Cell Reports, researchers at McGill University, Kyoto University and INSERM/University of Paris show that an organic compound produced by the intestinal flora, the metabolite 4-Cresol, exhibits protective effects against type 1 and type 2 diabetes by stimulating the proliferation and function of insulin-producing beta...
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How AI helps people with atrial fibrillation
Atrial fibrillation is an irregular and often rapid heart rate that can increase your risk of stroke and other heart-related complications. Up to 6.1 million people in the U.S. have the condition, according to the Centers for Disease Control and Prevention. Dr. Paul Friedman, a Mayo Clinic cardiologist, uses artificial intelligence (AI) to identify people...