by Walter and Eliza Hall Institute of Medical Research Walter and Eliza Hall Institute researchers have revealed a new vulnerability in lymphomas that are driven by one of the most common cancer-causing changes in cells. The team revealed that the protein MNT is required for the survival of lymphoma cells that are driven by the...
Post
Scientists identify drug fragments that could lead to new cancer drugs
by Institute of Cancer Research The SAM domain of Tankyrase self-assembles into structures resembling curled pearl strings. The image shows a representation of these structures, elucidated by X-ray crystallography. The background shows colorectal cancer cells stained for their cell nuclei (blue) and destruction complexes (red and green). Credit: Dr Sebastian Guettler, ICR. Researchers have found...
Post
Pill-sized ‘heater’ could increase accessibility in diagnosing infectious disease
Device developed at University of Toronto Engineering regulates the temperature of biological samples through different stages of diagnostic testing UNIVERSITY OF TORONTO FACULTY OF APPLIED SCIENCE & ENGINEERING Researchers at the University of Toronto Engineering have developed a tiny “heater” – about the size of a pill – that could allow resource-limited regions around the...
Post
New discovery has important implications for treating common eye disease
TRINITY COLLEGE DUBLIN Scientists from Trinity College Dublin have made an important discovery with implications for those living with a common, debilitating eye disease (age-related macular degeneration, AMD) that can cause blindness. They have discovered that the molecule TLR2, which recognises chemical patterns associated with infection in the body, also seems to play an important...
Post
Researchers show what drives a novel, ordered assembly of alternating peptides
NORTH CAROLINA STATE UNIVERSITY A team of researchers has verified that it is possible to engineer two-layered nanofibers consisting of an ordered row of alternating peptides, and has also determined what makes these peptides automatically assemble into this pattern. The fundamental discovery raises the possibility of creating tailored “ABAB” peptide nanofibers with a variety of...
Post
Language disorders as indicators of the diagnosis and progression of Huntington’s disease
A study shows that the first symptoms of the disease are revealed through linguistic changes in spontaneous speech UNIVERSITAT POMPEU FABRA – BARCELONA Huntington’s disease is a hereditary neurodegenerative disorder caused by a gene of chromosome 4 that affects a very important area of the brain, the striatum. People are born with the defective gene...
Post
New biomarkers for diagnosis and prognosis of lung cancer identified
Applying bioinformatics to resolve biological problems. This is the objective of the research group of the University of Malaga “BI4NEXT”, which, in one of its latest studies, developed in the Supercomputing and Bioinnovation Center (SCBI) based on biobank samples, has identified new biomarkers for the diagnosis, prognosis and even treatment of lung cancer. A discovery...
Post
A potential new weapon against deadly brain and soft tissue cancers
by University of Southern California Researchers at the USC Viterbi School of Engineering have designed a new drug cocktail that kills some types of brain and soft tissue cancers by tricking the cancer cells to behave as if they were starving for their favorite food—glucose. The researchers’ findings were recently published in the Journal of...
Post
New drug combination restores beta cell function in animal model
by Helmholtz Association of German Research Centres Cell nucleus in white, beta cells and insulin in green, alpha cells (hormone glucagon) in red and delta cells (hormone somatostatin) in magenta. Credit: Helmholtz Zentrum München / Aimée Bastidas-Ponce The loss of the identity of insulin-secreting beta cells in the islet of Langerhans, a process also called...
Post
Origins of immune system mapped, opening doors for new cancer immunotherapies
by Wellcome Trust Sanger Institute A first cell atlas of the human thymus gland could lead to new immune therapies to treat cancer and autoimmune diseases. Researchers from the Wellcome Sanger Institute, Newcastle University and Ghent University, Belgium, mapped thymus tissue through the human lifespan to understand how it develops and makes vital immune cells...