by Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.) Researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), working with an international network of scientists, have identified an inflammatory regulatory circuit in the eye controlled by a subtype of endothelial cell, those that line the interior of blood vessels. The discovery was made by analyzing...
Urgently needed: New way to combat vaccine-derived poliovirus
by Bob Yirka , Medical Xpress A team of researchers from the U.K., Switzerland, the U.S., and the Congo has found that there is an urgent need to combat a vaccine-derived poliovirus. In their paper published in the journal Science, the group describes their study of the vaccine-derived virus and what they found.. Polio in...
Research reveals why some prostate cancers are more aggressive
by University of East Anglia Researchers at the University of East Anglia have discovered why some prostate cancers are more aggressive, spread to different parts of the body, and ultimately cause death It is hoped that the discovery, published today, could transform patient treatment. The findings come after the same team developed a test that...
Newly identified biomarker offers fresh hope for early Alzheimer’s diagnosis
by Edith Cowan University A global team of researchers has discovered a new biomarker that could be used to detect Alzheimer’s disease decades before symptoms emerge. Alzheimer’s disease affects more than 340,000 Australians and it is well documented that early diagnosis is the best hope for effective treatment. The study, published in Nature Medicine, examined...
Scientists discover an early sign of type 2 diabetes: Misfolded proinsulin
by Monica May, Sanford Burnham Prebys Medical Discovery Institute Misfolded proinsulin—a protein the body normally processes into insulin—is an early sign of type 2 diabetes, according to a study by scientists at Sanford Burnham Prebys and the University of Michigan Medical School. The discovery, published in eLife, could lead to tests or treatments that help...
New study reveals how skin cells prepare to heal wounds
by University of California, Irvine A team of University of California, Irvine researchers have published the first comprehensive overview of the major changes that occur in mammalian skin cells as they prepare to heal wounds. Results from the study provide a blueprint for future investigation into pathological conditions associated with poor wound healing, such as...
Device could ‘hear’ disease through structures housing cells
PURDUE UNIVERSITY WEST LAFAYETTE, Ind. — Similarly to how a picked lock gives away that someone has broken into a building, the stiffening of a structure surrounding cells in the human body can indicate that cancer is invading other tissue. Monitoring changes to this structure, called the extracellular matrix, would give researchers another way to...
Researchers invent method to unlock potential of widely used drug
UNIVERSITY OF COPENHAGEN THE FACULTY OF HEALTH AND MEDICAL SCIENCES Sugars like polysaccharides are found everywhere in nature and are believed to be essential for life to arise. In humans, they cover the surface of all cells and the family of polysaccharides called GAGs (glycosaminoglycans) are particularly abundant and difficult to analyse. GAGs of the...
Antibiotic intercepts building blocks of the bacterial envelope
Research group of the University of Bonn solves a 30-year-old puzzle: The mode of action of daptomycin UNIVERSITY OF BONN One of the last arrows in the quiver in the fight against dangerous bacteria is the reserve antibiotic daptomycin. It is used primarily when conventional drugs fail due to resistant bacteria. Although the antibiotic was...
Removing belly fat before it sticks to you
University of Cincinnati researchers produce fat busting proteins in the laboratory UNIVERSITY OF CINCINNATI CREDIT: COLLEEN KELLEY/UNIVERSITY OF CINCINNATI Triglycerides, those fats that seem to be the bane of any diet, remain a mystery for many researchers. Plenty of them are in Big Macs, deep pan pizza and the like, but some are a necessity...