by Washington University School of Medicine Immunotherapy that involves treating cancer with the body’s own immune cells, or those of a matched donor, shows promise in clinical trials for some patients, but not all. A new study from Washington University School of Medicine in St. Louis suggests that the age of certain immune cells used...
Extract from seeds of the Melinjo tree may improve obesity and diabetes
Melinjo seed extract activates the physiologically beneficial substance adiponectin which improves obesity and diabetes KUMAMOTO UNIVERSITY In Southeast Asia, the fruit, flowers, and leaves of Indonesia’s “Melinjo” tree are traditional foods. Researchers from Kumamoto University, Japan who study plants from around the world for useful medicinal properties have found that Melinjo seed extract (MSE) stimulates...
Identifying fatty acid-binding protein 4 as a responsible gene for renal stone formation
Fatty acid-binding protein 4 downregulation drives calcification in the development of kidney stone disease NAGOYA CITY UNIVERSITY Kidney stone disease has a high prevalence worldwide, ranging up to 13% in North America, 9% in Europe, and 5% in Asia. They are painful for patients, often lead to surgery, and impart a significant economic impact. Many...
ACE inhibitors and angiotensin receptor blockers may increase the risk of severe COVID-19
LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER New Orleans, LA – James Diaz, MD, MHA, MPH & TM, Dr PH, Professor and Head of Environmental Health Sciences at LSU Health New Orleans School of Public Health, has proposed a possible explanation for the severe lung complications being seen in some people diagnosed with COVID-19. The manuscript...
New research may help older adults stay physically capable for longer
UNIVERSITY OF BIRMINGHAM Drug therapies that help older adults maintain their skeletal muscle mass and physical function for longer could be a step closer after researchers at the University of Birmingham identify a key mechanism that drives the clearance of damaged mitochondria. A team in the University’s School of Sport, Exercise and Rehabilitation Sciences are...
Study finds molecule in lymphatic system implicated in autoimmune diseases
HOSPITAL FOR SPECIAL SURGERY (New York City. March 20, 2020.) A study by investigators at Hospital for Special Surgery (HSS) has discovered a molecule in the lymphatic system that has the potential to play a role in autoimmune disease. The study, “Lymph node stromal CCL2 limits antibody responses,” was published online today in the journal...
Chip Measures Stiffness of Extracellular Matrix to Spot Disease
MEDGADGET EDITORSDIAGNOSTICS, MEDICINE, ONCOLOGY, PATHOLOGY Living cells inside our bodies are normally surrounded by an extracellular matrix, a supporting structure, that contains substances such as collagen and enzymes that help cells to function properly. When disease, particularly cancer, is present, the extracellular matrix tends to stiffen. This stiffening can be an indicator of disease arrival...
Stanford-led study shows kids exposed to TB at higher risk of disease than thought
Young children exposed to tuberculosis are at a surprisingly high risk of developing the disease, according to research led by the School of Medicine. The findings, which were published online in The Lancet, come from the largest modern study to assess TB risk among children closely exposed to the disease. TB kills more people than...
New drug target found for COVID-19
Scientists discover critical protein that lets virus hide from immune system. new potential drug target has been identified in SARS CoV-2 — the virus that causes COVID-19 — by scientists who say multiple drugs will be needed to treat the pandemic. Scientists from Northwestern University Feinberg School of Medicine have mapped the atomic structure of...
Tracer molecules can distinguish between very similar brain diseases
Two diseases that affect the brain, Parkinson’s disease and multiple system atrophy, show the same characteristics: proteins form toxic aggregates. Scientists have now shown that tracer molecules developed at LiU can distinguish between these diseases. They hope that the discovery will lead to earlier molecular diagnosis A doctor faced with a person who has problems...