NEW YORK (Reuters Health) – The single-tablet combination of darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) is effective for long-term viral suppression in previously untreated patients with HIV-1 infection, according to 96-week results from the AMBER trial. Week 48 primary analyses of the AMBER trial and the companion EMERALD trial showed that D/C/F/TAF had high, noninferior antiviral efficacy with...
Month: <span>April 2020</span>
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THE CORONAVIRUS HAS ALREADY MUTATED INTO 30+ STRAINS
BY DAN ROBITZSKI / APRIL 21 2020 New research suggests that SARS-CoV-2, the virus that causes COVID-19, could have already mutated into more than 30 separate strains. The study found that different strains can generate vastly different levels of viral load as others, the South China Morning Post reports, making them far more dangerous. One...
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Research, Underexplored until Recently, Could Produce Alzheimer’s Treatments
By Kenneth S. Kosik | Scientific American Research into the brain’s protein-disposal systems, electrical activity and three other areas looks promising Attempts to treat Alzheimer’s have floundered because scientists have spent too little time thinking deeply about the underlying biology of this ailment. Recent advances in understanding the brain’s protein-disposal systems, the role of inflammation,...
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A history of cannabis dependence associated with many negative mental health outcomes
More than 1% of Canadians have been dependent on cannabis at some point in their lives. Despite the fact that marijuana use is expected to grow with the recent legalization of recreational cannabis in Canada, little research has focused on factors associated with recovery from addiction. New research published online this month in the journal...
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Blood sugar levels may influence vulnerability to coronavirus
by Adam M. Brufsky, The Conversation Sugar is not only something that sweetens our food. It is also something that is an essential part of the proteins that make up our bodies. That led me to believe, as I wrote in the Journal of Medical Virology, that control of blood glucose by diet and exercise,...
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Worm study offers new insight into link between obesity and poor sleep
By Rich Haridy For years, observational studies have linked short sleep patterns with obesity, and many scientists suspect it is the sleep irregularities causing metabolic dysfunction and appetite disruptions. New research from the University of Pennsylvania’s Perelman School of Medicine and the University of Nevada, Reno, investigating sleep in a laboratory worm model is suggesting...
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Orujo olive oil reduces obesity
Researchers from the Department of Pharmacology, Paediatrics and Radiology at the University of Seville, in collaboration with Dr. Rodriguez from the International University of Catalonia, have confirmed that Orujo Olive OIL (POCTA), when introduced into the diet, produces a significant reduction in obesity and vascular and inflammatory complications in obese mice. In addition, given that...
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Study identifies potential drug treatments for telomere diseases
April 22, 2020 — A new qualitative study by researchers at Columbia University Mailman School of Public Health found that the majority of women living with HIV would endorse a monthly long acting injectable (LAI) antiretroviral therapy over current daily pills. LAI HIV therapy has completed Phase III trials and is awaiting Food and Drug...
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Study identifies potential drug treatments for telomere diseases
by Children’s Hospital Boston Capping decades of research, a new study may offer a breakthrough in treating dyskeratosis congenita and other so-called telomere diseases, in which cells age prematurely. Using cells donated by patients with the disease, researchers at the Dana-Farber/Boston Children’s Cancer and Blood Disorders Center identified several small molecules that appear to reverse...
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Novel imaging application illuminates processes in cancer, COVID-19 and other diseases
by Brian Burns, Massachusetts General Hospital Medical images for a wide range of diseases, including coronavirus 19 (COVID-19), can now be more easily viewed, compared, and analyzed using a breakthrough web-based imaging platform developed by Massachusetts General Hospital (MGH) and collaborating researchers. The Open Health Imaging Foundation (OHIF) web viewer was originally developed with grant...