This article by Dr. Vivekanandan Palaninathan et al. is published in Current Pharmaceutical Design, 2020 BENTHAM SCIENCE PUBLISHERS Direct reprogramming or Transdifferentiation is a way of inducing changes in the cell type from one lineage into another lineage, bypassing pluripotency. This approach is an innovative choice to replace the lost cardiomyocytes after an end-stage myocardial...
Vitamin D may help prevent a common side effect of anti-cancer immunotherapy
New research indicates that taking vitamin D supplements may help prevent a potentially serious side effect of a revolutionary form of anti-cancer therapy. The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer Society (ACS). Immune checkpoint inhibitors help the immune system recognize and combat cancer cells, and although these...
COVID-19 NEW Update: Asians Have Highest COVID-19 Death Risks Over Eating Too Much Sugar
The University of Edinburgh in Great Britain claims Asians are more likely to die in Coronavirus compared to other races, specifically South Asian. One of the main arguments that supported this claim is the fact that this race also shown increase cases in diabetes. Therefore, treating patients with both these diseases may have a more...
Parkinson’s linked to overabundance of opportunistic gut pathogens
By Nick Lavars June 21, 2020 As a disease without a cure or means of prevention, there is a lot we don’t know about Parkinson’s and the way it takes hold in the human body. One school of thought is that it actually begins in the gut, and a new study has strengthened these ties...
Cancer vaccine hope: Personalised treatment designed to boost the body’s natural ability to fight the disease shows ‘promising signs’ in clinical trials
By RYAN MORRISON FOR MAILONLINE Researchers take a biopsy of a cancerous tumour to look for certain proteins Each patient has a ‘different cancer’ and the treatment is specifically targeted It is given alongside chemotherapy drugs to boost the body’s immune response So far only eight per cent of patients saw their tumour reduce but...
Scientists investigate a powerful protein behind antibody development
become T follicular helper cells (Tfh cells, shown in blue), which work with B cells (shown in green) to produce powerful antibodies. Activated B cells give rise germinal centers (shown in red), where mature B cells proliferate and produce highly specific antibodies against pathogens. Bcl6 blocks the expression of two proteins that normally stop Tfh...
Biomarker test highly accurate in detecting early kidney cancer
by Dana-Farber Cancer Institute A novel liquid biopsy method can detect kidney cancers with high accuracy, including small, localized tumors which are often curable but for which no early detection method exists, say scientists from Dana-Farber Cancer Institute. The report in Nature Medicine suggests that if validated in larger trials and applied widely, the non-invasive...
Nuclear softening allows cells to move into dense tissue, encouraging injury repair
by Perelman School of Medicine at the University of Pennsylvania By softening a cell’s nucleus so that it can squeeze its way through dense connective tissues, a group of researchers believe they’ve demonstrated a new way to help the body efficiently repair injuries. The team of researchers from the University of Pennsylvania tested this theory...
Urine test reveals quality of your diet — and whether it’s the best fit for your body
Scientists have completed large-scale tests on a new type of five-minute urine test that measures the health of a person’s diet, and produces an individual’s unique urine ‘fingerprint’. Scientists have completed large-scale tests on a new type of five-minute urine test that measures the health of a person’s diet, and produces an individual’s unique urine...
Focused ultrasound shows promise against deadliest brain tumor
UNIVERSITY OF VIRGINIA HEALTH SYSTEM NEUROSURGEON JASON SHEEHAN, MD, PHD, OF UVA HEALTH, IS PIONEERING THE USE OF FOCUSED ULTRASOUND TO TREAT GLIOBLASTOMA, THE DEADLIEST BRAIN TUMOR.view more CREDIT: UVA HEALTH An innovative use of focused ultrasound being pioneered at the University of Virginia School of Medicine is showing promise against glioblastoma, the deadliest brain...