by American Heart Association Credit: CC0 Public Domain High blood pressure appears to accelerate a decline in cognitive performance in middle-aged and older adults, according to new research published today in Hypertension. Nearly half of American adults have high blood pressure or hypertension. Having high blood pressure is a risk factor for cognitive decline, which includes such things as...
TOKYO MEDICAL AND DENTAL UNIVERSITY VASH1 exerts anti-angiogenic effects through the inhibition of receptor endocytosis by ?Y-tubulin increases. VEGF and FGF2 induce endocytosis of their own receptors, VEGFR2 and FGFR1, respectively, along MTs. This is important for VEGF (FGF2)-signaling activation and pro-angiogenic effects. VASH1 induces the generation of ?Y-tubulin-rich MTs (excessive ?Y-tubulin levels), leading to...
A team of researchers led by the University of Wisconsin–Madison professor David Gamm is developing a transplantable retinal patch intended to help restore vision to military personnel blinded in the line of duty and to treat individuals with degenerative eye diseases such as macular degeneration. Retina is the only part of the central nervous system...
The discovery can help to cure bacterial infections without inducing resistance or causing harm to good bacteria. Researchers from the Antimicrobial Resistance (AMR) Interdisciplinary Research Group (IRG) at Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, have developed a method to produce customizable engineered lysins that can be used to selectively kill bacteria of interest...
By Erin Michael Numerous studies have provided evidence supporting the use of ivermectin to prevent and treat COVID-19, according to the Frontline COVID-19 Critical Care Alliance. Paul Marik, MD, FCCM, FCCP, founder of the alliance and a professor and chief of the division of pulmonary and critical care medicine at Eastern Virginia Medical School, said that...
Since the onset of the disease, more than 40.5 million people have been diagnosed with COVID-19 and nearly 1.2 million people have died (October 21, 2020). There is no complete understanding of the pathogenesis of SARS-CoV-2 infection and to this day there is no specific therapy or vaccine available. Thus, patient care is based on...
by University of Helsinki Credit: University of Helsinki Findings from the FinnGen study encompassing 120,000 women indicate that inherited breast cancer risk should be assessed in an increasingly comprehensive manner. Currently, only individual gene mutations are taken into consideration in breast cancer therapy and prevention. The study demonstrates that more extensive genomic data can be used...
by University of Exeter Credit: CC0 Public Domain Pioneering new research has made a pivotal breakthrough that dispel concerns that human stem cells could contain cancer-causing mutations. A team of scientists from the University of Exeter’s flagship Living Systems Institute has shown that stem cells contain no cancer mutations when they are grown in their most primitive or...
by University of Utah Health Sciences Credit: CC0 Public Domain Massive “plumes” of glutamate, a key neurotransmitter, surging in the brain could help explain the onset of migraine with aura—and potentially a broad swath of neurologic disease, including stroke and traumatic brain injury—according to an international study led by University of Utah Health scientists. The study,...
by UT Southwestern Medical Center Sherwood Brown, M.D., Ph.D. Credit: UT Southwestern Medical Center Recently published UT Southwestern research reveals new insights about risk factors for depression based on data from a landmark longitudinal study focused on heart disease. One study, published in the Journal of Clinical Psychiatry, shows a link between an inflammatory molecule in the...
