by André Julião, FAPESP In experiments by Brazilian researchers with mice and tumor cell lines, the drug showed potential to combat metastasis. The scientists are planning to conduct clinical trials with patients who are on chemotherapy (representative liver sections of control (c-e) or ambrisentan-treated (f, g) mice are shown, with small red circles indicating tumor metastatic foci. The...
by A’ndrea Elyse Messer, Pennsylvania State University Section of a brain showing neurons that have nNOS-expressing neurons labeled in green, DREADD-expressing neurons in magenta. Neurons that express both show up as white. Credit: Jordan Norwood, Penn State Neurons control blood flow in tiny vessels in the brain, but researchers know little about this relationship. Now a...
VIRGINIA COMMONWEALTH UNIVERSITY IMAGE: NEW RESEARCH FINDINGS FROM PAULA BOS, PH.D., IDENTIFIED A TYPE OF IMMUNE CELLS THAT ACTS AS A MAJOR DRIVER OF BREAST CANCER GROWTH BY PREVENTING THE ACCUMULATION OF A SPECIFIC PROTIEN THAT INDUCES ANTI-TUMOR RESPONSES. CREDIT: VCU MASSEY CANCER CENTER Breast cancer is the most common cancer in women worldwide, but...
by Tokyo University of Science Credit: CC0 Public Domain As humans evolve, cancer also evolves in parallel, making the race for finding efficient treatment methods for cancer patients challenging and constant. In addition to designing drugs for treatment, the delivery of these drugs to targeted organs is also a major challenge faced by the cancer research...
ELIFE A drug that boosts the removal of cellular debris in immune cells may increase the protective effects of vaccines in older adults, a study published today in eLife shows. The results may lead to new approaches to protect older individuals from viruses such as the one causing the current COVID-19 pandemic and influenza. “Older adults are...
UNIVERSITY OF COLORADO ANSCHUTZ MEDICAL CAMPUS AURORA, Colo. (Dec. 15, 2020) – Researchers at the University of Colorado Anschutz Medical Campus have discovered that fructose stimulates the release of vasopressin, a hormone linked to obesity and diabetes. They also found that water can suppress the hormone and alleviate these conditions in mice. “The clinical significance of this...
by Purdue University Bioengineered lactobacillus (red) interacts with surface heat shock protein 60 (white, yellow arrows), blocking Listeria monocytogenes (green, white arrows) from crossing into the bloodstream. Credit: Rishi Drolia and Arun Bhunia For pregnant women, the elderly and those with weakened immune systems, listeriosis is a serious foodborne illness often linked to deli meats, fresh...
BRIGHAM AND WOMEN’S HOSPITAL With nearly 2 million Americans battling type 1 diabetes, it is no surprise that clinical therapies for the disease are constantly evolving and improving. In type 1 diabetes mellitus, the body’s immune system attacks and destroys insulin-producing β-cells. As a result, people living with type 1 diabetes lose insulin secretion and...
by Tufts University Credit: Pixabay A protein that functions like the vintage video game Pac-Man, eating toxic cellular waste caused by high sugar intake, is itself compromised by a sugary diet, according to the results of a study in mice with potential implications for humans. The study, led by a research team at Tufts University joined by researchers at eight...
By Nick Paul Taylor India’s Subject Expert Committee (SEC) has asked to see additional data on AstraZeneca’s COVID-19 vaccine before deciding whether to grant emergency use authorization (EUA). The Central Drugs Standard Control Organization (CDSCO) wants to see immunogenicity data from patients in the UK and India and safety data beyond the 14 November cut-off shared...
