DECEMBER 3RD, 2020 CONN HASTINGS Researchers at Imperial College London have developed a tiny lab-on-a-chip that can perform PCR diagnostics in just a few minutes. Usually requiring bulky and expensive lab equipment, PCR is a gold standard diagnostic test for a variety of infectious pathogens, including bacteria and viruses, such as SARS-CoV-2. The new testing device...
NEW ROLE FOR ULTRASOUND: IMAGING LUNGS
Advances in technique and technology have made ultrasound increasingly valuable for imaging a wide variety of medical applications, including pulmonary disease. That’s remarkable, in part, because it was once thought that ultrasound, which most people associate with pregnant mothers and prenatal check-ups, would never be useful in assessing lung health. And it’s important because it can improve...
β-AR agonist therapy puts the brakes on oral cancer progression
TOKYO MEDICAL AND DENTAL UNIVERSITY IMAGE: IN THIS STUDY WE IDENTIFIED ISOXSUPRINE, A Β2-ADRENERGIC RECEPTOR AGONIST AS AN EFFECTIVE INHIBITOR OF MESENCHYMAL PHENOTYPES AND MIGRATION OF ORAL SQUAMOUS CELL CARCINOMA CELLS SUGGESTING THAT Β2-ADRENERGIC RECEPTOR SIGNAL. CREDIT: DEPARTMENT OF BIOCHEMISTRY,TMDU Researchers from Tokyo Medical and Dental University (TMDU) find that stimulating a group of cellular...
Low-dose CT for lung cancer screening: benefit outweighs potential harm
INSTITUTE FOR QUALITY AND EFFICIENCY IN HEALTH CARE For heavy (ex-)smokers, lung cancer screening using low-dose computed tomography (low-dose CT, LDCT) offers more benefit than harm: The procedure can save a number of people from dying of lung cancer; for some of them, it might also prolong overall survival. This is the conclusion drawn by...
New updates to federal guidelines revamp asthma management
Posted Today Updates to six key areas of asthma care focus on improving diagnosis, management and treatment. The National Institutes of Health today announced 19 recommendations in six key areas of asthma diagnosis, management and treatment. The new guidance, published in the Journal of Allergy and Clinical Immunology, represents the first updates to federal comprehensive asthma management and treatment...
Kidney injury in diabetic ketoacidosis linked to brain injury
by Children’s Hospital of Philadelphia Credit: CC0 Public Domain Researchers from a consortium of hospitals including Children’s Hospital of Philadelphia (CHOP) have identified factors that make children with diabetic ketoacidosis more likely to experience acute kidney injury. Analyzing data from a large, multicenter clinical trial, the researchers also found that children who experience acute kidney injury are more...
Digital breast tomosynthesis improves invasive cancer detection
RADIOLOGICAL SOCIETY OF NORTH AMERICA IMAGE: IMAGES SHOW SYMPTOMATIC FALSE-NEGATIVE CANCER IN A 73-YEAR-OLD BLACK WOMAN WHO PRESENTED WITH A PALPABLE ABNORMALITY 64 DAYS AFTER NEGATIVE SCREENING MAMMOGRAPHY. CREDIT: RADIOLOGICAL SOCIETY OF NORTH AMERICA OAK BROOK, Ill. (December 4, 2020) – Breast cancer screening with digital breast tomosynthesis (DBT) offers significant advantages over digital mammography,...
Why COVID outbreaks look set to worsen this winter
It’s too soon to say whether COVID is seasonal like the flu — but where clusters aren’t under control, infections will continue to swell. Smriti Mallapaty Changing seasons might affect the transmission of SARS-CoV-2, but researchers say it’s too early to tell.Credit: Beata Zawrzel/NurPhoto/Getty Winter is fast approaching in the Northern Hemisphere, and researchers warn...
For people with certain BRCA mutations, activating the immune system could be promising treatment
MEMORIAL SLOAN KETTERING CANCER CENTER Treatments that harness the immune system to fight cancer have greatly improved outcomes for some people with cancer. Scientists are learning more about why some people respond much better than others to these drugs. One major factor is something called tumor mutation burden (TMB) — the number of DNA changes...
Drug reverses age-related cognitive decline within days
by University of California, San Francisco Credit: CC0 Public Domain Just a few doses of an experimental drug can reverse age-related declines in memory and mental flexibility in mice, according to a new study by UC San Francisco scientists. The drug, called ISRIB, has already been shown in laboratory studies to restore memory function months after...