by Georgetown University Medical Center Scanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Immune-system T cells have been reprogrammed into regenerative stem cell-like memory (TSCM) cells that are long-lived, highly active “super immune cells” with strong antitumor activity, according to new research from Georgetown Lombardi...
JAX, UMaine-lead team discover new connection between Alzheimer’s dementia and Dlgap2
UNIVERSITY OF MAINE A gene known for helping facilitate communication between neurons in the nervous system has been discovered to be connected with Alzheimer’s dementia and cognitive decline, according to a national research team led by The Jackson Laboratory and University of Maine. Catherine Kaczorowski, associate professor and Evnin family chair in Alzheimer’s research at The Jackson Laboratory (JAX),...
The drug aprotinin inhibits entry of SARS-CoV2 in host cells
GOETHE UNIVERSITY FRANKFURT FRANKFURT. The surface of the SARS-CoV-2 virus is studded with spike proteins. The virus needs these in order to dock onto proteins (ACE2 receptors) on the surface of the host cell. Before this docking is possible, parts of the spike protein have to be cleaved by the host cell’s enzymes – proteases....
Damaged Sense of Smell in Covid Patients Holds Clues to How Recovery Might Work
Researchers study neurological reasons why some coronavirus patients often find familiar scents repulsive Brenda Jenkins, a catering chef in Manhattan, lost her sense of smell completely in mid-March after exposure to the coronavirus on a cooking job. Scientists are uncovering clues to explain how the coronavirus attacks the nervous system by studying a bizarre side effect...
Scientists Say They’ve Partially Reversed a Cellular Aging Process in Humans
MIKE MCRAE; 20 NOVEMBER 2020 Every time a cell inside your body replicates, a slither of your youth crumbles to dust. This occurs via the shortening of telomeres, structures that ‘cap’ the tips of our chromosomes. Now, scientists in Israel say they’ve been able to reverse this process and extend the length of telomeres in a...
Researchers have developed an app against needle fear
by Tilburg University People in the Netherlands will soon have the opportunity to receive vaccination against COVID-19. However, an estimated 35% of all people suffer from needle fear. Elisabeth Huis in ‘t Veld of the Tilburg School of Humanities and Digital Sciences has developed a game app which, based on thermal images of the face, can...
Early, late stages of degenerative diseases are distinct, study shows
by Jade Boyd, Rice University Based on thousands of experiments over more than a decade, Rice University biochemists Michael Stern and James McNew believe degenerative diseases as varied as Alzheimer’s, Parkinson’s and muscle atrophy occur in two phases (green and red) marked by distinct alterations in the activity of the signaling pathway proteins TOR, AMPK, Foxo...
BICRA gene provides answers to patients, doctors and scientists
by Molly Chiu, Baylor College of Medicine Researchers identified the BICRA gene’s involvement in neural development. Physicians and scientists are constantly on the lookout for new disease genes that can help them understand why patients have undiagnosed medical problems. Often the first clues come from genetic testing that reveals a change or mutation in a gene...
Sound waves power new advances in drug delivery and smart materials
RMIT UNIVERSITY IMAGE: THE PATENTED ‘RESPITE’ NEBULISER USES HIGH-FREQUENCY SOUND WAVES TO PRECISELY DELIVER DRUGS TO THE LUNGS. Researchers have revealed how high-frequency sound waves can be used to build new materials, make smart nanoparticles and even deliver drugs to the lungs for painless, needle-free vaccinations. While sound waves have been part of science and medicine...
World’s first: Drug guides stem cells to desired location, improving their ability to heal
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE IMAGE: NEURAL STEM CELLS MATURING INTO ASTROCYTES (YELLOW). Scientists at Sanford Burnham Prebys Medical Discovery Institute have created a drug that can lure stem cells to damaged tissue and improve treatment efficacy–a scientific first and major advance for the field of regenerative medicine. The discovery, published in the Proceedings of the National...