For the first time, scientists have come up with a precise atomic-level explanation for why glulisine- a commonly used medication to treat diabetes- is faster acting than insulin. The findings, published in Scientific Reports, could have benefits for diabetes patients in ensuring that more improved insulin can be developed for future treatment. Image credit: Reversing Your...
Fisetin is perhaps the most intriguing of the first generation senolytic compounds, those capable of selectively destroying senescent cells in old tissues and thus producing rejuvenation to a meaningful degree. Senolytics have been demonstrated in animal studies to reverse many age-related conditions to a greater degree than any other approaches. Why is fisetin intriguing? Because in mice, it appears to be about...
AMERICAN INSTITUTE OF PHYSICS IMAGE: Biomedical engineers have developed a technique to observe wound healing in real time, discovering a central role for cells known as fibroblasts. The work is the first demonstration of a wound closure model within human vascularized tissue in a petri dish. This image shows steps in wound healing in a...
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE IMAGE: PETER ADAMS, PH.D., PROFESSOR IN THE TUMOR INITIATION AND MAINTENANCE PROGRAM AT SANFORD BURNHAM PREBYS’ NCI-DESIGNATED CANCER CENTER. CREDIT: SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE LA JOLLA, CALIF. – Jan 20, 2020 – Scientists have identified two drugs that are potent against acute myeloid leukemia (AML) when combined,...
by Mandy Armitage, MD, January 13,2021 Key takeaways: You should still wear your mask and keep your distance from others after you have been vaccinated. We don’t know yet how well the COVID-19 vaccines reduce the spread of the virus. Almost 9 million people in the U.S. have received at least one dose of a COVID-19 vaccination,...
Reviewed by Emily Henderson, B.Sc. Jan 21 2021 Breast cancer is the second most common cancer among women in the United States, and cigarette smoking is associated with a higher incidence of breast cancer spread, or metastasis, lowering the survival rate by 33% at diagnosis. While cigarette smoking’s link to cancer is well-known, the role...
UNIVERSITY OF QUEENSLAND IMAGE: BACTERIA GROWING IN THE SHAPE OF THE SYNTHETIC CANNABIDIOL MOLECULE. CREDIT: INSTITUTE FOR MOLECULAR BIOSCIENCE, UNIVERSITY OF QUEENSLAND. Synthetic cannabidiol, better known as CBD, has been shown for the first time to kill the bacteria responsible for gonorrhoea, meningitis and legionnaires disease. The research collaboration between The University of Queensland and Botanix Pharmaceuticals Limited could lead to...
NATIONAL RESEARCH COUNCIL OF SCIENCE & TECHNOLOGY IMAGE: REPRESENTATIVE TRAJECTORIES FOR STROKE MODEL RATS TREATED WITH SHAM AND TFUS, COMPARED TO A HEALTHY RAT (BOTTOM ROW) CREDIT: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY(KIST) Cerebral infarction, commonly known as ischemic stroke, has a high mortality rate and causes severe damage to nervous cells in the brain owing to...
INNOVATION CENTER OF NANOMEDICINE Summary Ultra-small nanomedicines of approximately 18 nm were fabricated by dynamic ion-pairing between Y-shaped block copolymers and nucleic acid drugs, such as siRNA and antisense drugs. Chemically modified and double-stranded oligonucleotides dramatically enhanced the stability of the ultra-small nanomedicines in the blood circulation. The ultra-small size allows for high permeability in...
by Northwestern University Credit: CC0 Public Domain As the air continues to dry and temperatures drop, the yearly battle against dry hands and skin has officially begun. New research from Northwestern University has found new evidence deep within the skin about the mechanisms controlling skin repair and renewal. Skin’s barrier function gives it the unique ability to fight...
