NATIONAL RESEARCH COUNCIL OF SCIENCE & TECHNOLOGY IMAGE: A SCHEMATIC DIAGRAM OF THE APPLICATION OF CANCER-TARGETED SUPERMOLECULAR PEPTIDE PHOTOTHERAPY DRUGS TO ANIMAL EXPERIMENTS DEVELOPED BY KIST RESEARCHERS. A SINGLE SUPERMOLECULAR PEPTIDE PHOTOTHERAPY INJECTION AND REPEATED PHOTOTHERAPY WERE USED TO COMPLETELY TREAT CANCER. CREDIT: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY(KIST) Researchers in South Korea have developed a phototherapy technology...
How the brain paralyzes you while you sleep
UNIVERSITY OF TSUKUBA IMAGE: HOW THE BRAIN PARALYZES YOU WHILE YOU SLEEP CREDIT: UNIVERSITY OF TSUKUBA Tsukuba, Japan — We laugh when we see Homer Simpson falling asleep while driving, while in church, and while even operating the nuclear reactor. In reality though, narcolepsy, cataplexy, and rapid eye movement (REM) sleep behavior disorder are all...
Smoking directly linked to a higher risk of subarachnoid hemorrhage
by American Heart Association Credit: CC0 Public Domain Adults who smoke or who are genetically predisposed to smoking behaviors are more likely to experience a serious type of stroke called subarachnoid hemorrhage (SAH), according to new research published today in Stroke, a journal of the American Stroke Association, a division of the American Heart Association. The results of this...
Clinical trial finds vitamin D does not ward off colds and flu
by QIMR Berghofer Medical Research Institute Credit: QIMR Berghofer Medical Research Institute A QIMR Berghofer-led randomized controlled trial of vitamin D supplements has found they do not protect most people from developing colds, flus and other acute respiratory infections. The trial, which is the largest of its kind to study the relationship between vitamin D and respiratory infection to...
Johnson & Johnson’s one-dose COVID vaccine promising in early trial
JANUARY 14, 2021 A single-shot COVID-19 vaccine from Johnson & Johnson has shown very strong results in early clinical trials, potentially providing a significant boost to U.S. vaccination efforts. The vaccine produced an immune response of all 805 clinical trial participants within two months of inoculation, according to results published Jan. 13 in the New England Journal of Medicine. The...
A new strategy for making blood stem cells healthier
by Albert Einstein College of Medicine Credit: CC0 Public Domain The hematopoietic (blood-forming) stem cells (HSCs) residing in our bone marrow produce all of our blood cells, including key immune cells that protect us from bacteria and viruses. As we age, our HSCs become less efficient and less able to make healthy new blood cells. In...
Discovery of a new form of a brain protein has clinical implications
by Ellen Goldbaum, University at Buffalo Diagram of the NMDA receptor protein (cyan) on the left illustrates its closed conformation; diagram on the right illustrates the open conformation, discovered by UB researchers. Credit: Han Wen A new study by University at Buffalo researchers has revealed that the absence of a single interaction within a brain receptor reduces its activity....
What if a pill could lower cholesterol like pricey injectables? Esperion intends to find out
By DAMIAN GARDE JANUARY 13, 2021 Reprints The most powerful cholesterol drugs ever invented have become a pharmaceutical cautionary tale, failing to reach their commercial potential because of high sticker prices and an inconvenient need for needles. Esperion Therapeutics (ESPR), a small Michigan company with a pair of approved cholesterol treatments, believes it can replicate...
Memory may be preserved in condition with brain changes similar to Alzheimer’s disease
by American Academy of Neurology Credit: Unsplash/CC0 Public Domain Primary progressive aphasia is a rare neurodegenerative condition characterized by prominent language problems that worsen over time. About 40% of people with the condition have underlying Alzheimer’s disease. But a new study has found that people with the condition may not develop the memory problems associated with...
Tiny molecules with a big impact
by BIH at Charité Influence of genetic variants on metabolite concentration: the higher the line, the greater the statistical probability that the genetic variants actually have an influence. Colors indicate the biochemical classes of the molecules. Credit: BIH/Maik Pietzner The human organism requires a variety of small molecules, such as sugars or fats, in order...