by Stowers Institute for Medical Research Adult mouse eye morphology. Credit: Ting Xie Lab What if the degenerative eye conditions that lead to glaucoma, corneal dystrophy, and cataracts could be detected and treated before vision is impaired? Recent findings from the lab of Investigator Ting Xie, Ph.D., at the Stowers Institute for Medical Research point to the ciliary body...
Study suggests compound protects myelin, nerve fibers
by Erik Robinson, Oregon Health & Science University Credit: CC0 Public Domain A compound developed at Oregon Health & Science University appears to protect nerve fibers and the fatty sheath, called myelin, that covers nerve cells in the brain and spinal cord. The discovery, published in the Journal of Neuroimmunology, could be important in treating or preventing...
Combination treatment for methamphetamine use disorder shows promise in new study
by NIH/National Institute on Drug Abuse Dr. Madhukar Trivedi and staff of UT Southwestern Medical Center conduct lab research. Credit: UT Southwestern Medical Center A combination of two medications, injectable naltrexone and oral bupropion, was safe and effective in treating adults with moderate or severe methamphetamine use disorder in a double-blind, placebo-controlled Phase III clinical trial....
APL-106 (uproleselan) Granted Breakthrough Therapy Designation in China for the Treatment of Acute Myeloid Leukemia
Apollomics, Inc., an innovative biopharmaceutical company committed to the discovery and development of mono- and combination- oncology therapies, and GlycoMimetics (Nasdaq: GLYC), announced APL-106 (uproleselan) has been granted Breakthrough Therapy Designation (BTD) from the China National Medical Products Administration (NMPA) Center for Drug Evaluation (CDE) for the treatment of relapsed/refractory acute myeloid leukemia (AML). Bone...
Painkiller-dispensing patch could be an alternative to opioids
By Ben Coxworth January 12, 2021 Potentially addictive opioid painkillers are frequently prescribed to patients recovering from surgery, but a new implantable patch may make them unnecessary wollertz/DepositphotosVIEW 1 IMAGES In order to keep patients from developing opioid addictions, it’s best if doctors can avoid prescribing the things in the first place. A new surgical patch...
COVID-19 blood plasma therapy ineffective in severely ill patients
By Rich Haridy January 12, 2021 Treating current COVID-19 patients with antibody-containing blood plasma from people who have recovered from the disease continues to be studied Flydragonfly/Deposit photos VIEW 1 IMAGES Early findings from a large international clinical trial suggest severely ill COVID-19 patients do not benefit from an experimental therapy involving infusions of blood...
Phage viruses can make superbugs susceptible to antibiotics again
By Michael Irving January 12, 2021 Researchers have found that bacteria-killing viruses could help make superbugs susceptible to antibiotics once again iLexx/Deposit photos VIEW 1 IMAGES Viruses firmly hold the world’s attention at the moment, but we shouldn’t ignore the rising health threat that bacteria pose, too. The crafty critters are fast evolving resistance to...
Scientists reveal mechanism that causes irritable bowel syndrome
KU LEUVEN IMAGE: ABOUT 20% OF PEOPLE SUFFER FROM IBS. CREDIT: POLINA ZIMMERMAN KU Leuven researchers have identified the biological mechanism that explains why some people experience abdominal pain when they eat certain foods. The finding paves the way for more efficient treatment of irritable bowel syndrome and other food intolerances. The study, carried out in mice...
Medication shows promise for weight loss in patients with obesity, diabetes
THE OBESITY SOCIETY SILVER SPRING, Md.–A new study confirms that treatment with Bimagrumab, an antibody that blocks activin type II receptors and stimulates skeletal muscle growth, is safe and effective for treating excess adiposity and metabolic disturbances of adult patients with obesity and type 2 diabetes. “These exciting results suggest that there may be a...
Lipid biomarkers in urine can determine the type of asthma
KAROLINSKA INSTITUTET IMAGE: SVEN-ERIK DAHLÉN, PROFESSOR AT THE INSTITUTE OF ENVIRONMENTAL MEDICINE, KAROLINSKA INSTITUTET. CREDIT: MATTIAS AHLM In a new study, researchers at Karolinska Institutet in Sweden have used a urine test to identify and verify a patient’s type of asthma. The study, which has been published in the American Journal of Respiratory and Critical Care Medicine, lays...