by Medical Research Council Credit: CC0 Public Domain Early treatment with an asthma drug budesonide shortens recovery time in COVID-19 patients aged over 50 who are treated at home or in other community settings. The Platform Randomized Trial of Interventions against COVID-19 in Older People (PRINCIPLE) trial is led by the University of Oxford. It is...
Web-delivered exercise and tailored texts improve knee arthritis therapy
by Cheryl Critchley, University of Melbourne Credit: CC0 Public Domain A new online program enhanced by text messages to help people with knee osteoarthritis exercise has been found to improve knee pain, physical function and quality of life, new research reveals. The University of Melbourne-led study developed and tested a free 24-week exercise program combining a...
Drug testing approach uncovers effective combination for treating small cell lung cancer
by National Institutes of Health Killer T cells surround a cancer cell. Credit: NIH Researchers from the National Institutes of Health have identified and tested a drug combination that exploits a weakness in small cell lung cancer (SCLC), an aggressive, dangerous cancer. The scientists targeted a vulnerability in how the cancer cells reproduce, increasing already high...
Artificial intelligence can accelerate clinical diagnosis of fragile X syndrome
by Peter Jurich, University of Wisconsin-Madison Credit: Pixabay/CC0 Public Domain An analysis of electronic health records for 1.7 million Wisconsin patients revealed a variety of health problems newly associated with fragile X syndrome, the most common inherited cause of intellectual disability and autism, and may help identify cases years in advance of the typical clinical diagnosis. Researchers from...
Cancer DNA blood tests validated by international research team
by Garvan Institute of Medical Research 3D-model of DNA. Credit: Michael Ströck/Wikimedia/ GNU Free Documentation License An international team today reports the findings of an independent assessment of five commercially-available assays for tumor DNA sequencing—a fast, cheap and less invasive method to diagnose and monitor cancer. The researchers revealed that all assays could reliably detect so-called...
TRAUMATIC MEMORIES COULD REDUCE THEIR IMPACT
The group’s findings suggest that procedures used by clinicians to indirectly reactivate traumatic memories render a window whereby those memories can be altered, or even erased completely, says Stephen Maren, professor of psychological and brain sciences at Texas A&M University. In therapy, imaginal reminders are often used to safely retrieve traumatic memories of experiences. For example, Maren says...
Fighting dementia with play
Cognitive motor training helps in the fight against Alzheimer’s and dementia, as demonstrated for the first time in a study by an international team of researchers with ETH Zurich involvement. The training platform used was developed by an ETH Zurich spin-off. Cognitive motor training helps in the fight against Alzheimer’s and dementia, as demonstrated for...
Research identifies gender bias in estimation of patients’ pain
“On a scale of one to 10, how much pain are you in?” In a recent study published by the Journal of Pain, co-authored by Elizabeth Losin, assistant professor of psychology and director of the Social and Cultural Neuroscience lab at the University of Miami, researchers found that a patient’s pain responses may be perceived differently by others...
Neural plasticity depends on this long noncoding RNA’s journey from nucleus to synapse
by The Scripps Research Institute Synaptic activation promotes a signaling cascade that results in the expression of long noncoding RNA, ADEPTR. It’s quickly transported along dendrites to synapses, where it acts on proteins involved in remodeling. Credit: Jenna Wingfield and Yibo Zhao of the Puthanveettil lab at Scripps Research in Jupiter, Florida. Making memories involves more than seeing friends or...
New understanding of the deleterious immune response in rheumatoid arthritis
by Monash University Researchers within the Biomedicine Discovery Institute at Monash University have made a breakthrough in understanding the role played by high-risk immune genes associated with the development of rheumatoid arthritis (RA). Credit: Erica Tandori Researchers within the Biomedicine Discovery Institute at Monash University have made a breakthrough in understanding the role played by high-risk immune genes...