by Sarah Amandolare Body mass index may be more helpful in predicting the risk of a common type of irregular heartbeat in women, while waist size may better predict that risk in men, new research suggests. The link between obesity and atrial fibrillation, or AFib—when the heart beats irregularly and often too fast—is well established. But researchers wanted to understand the...
by City University of Hong Kong CityU Researcher (Hu Jianyang) displays the microscopic image of the 3D breast cancer cell line derived from a patient’s tumor. Credit: City University of Hong Kong Triple-negative breast cancer (TNBC) is an aggressive type of breast cancer with a high fatality rate. Currently, chemotherapy is the major treatment option,...
by Bob Yirka , Medical Xpress In an interventional RCT, the role of histamine H1/H2 receptor signaling for exercise training adaptations was investigated. By chronic blockade of histamine H1/H2 receptors in humans, we show that integrative adaptations related to insulin sensitivity, vascular function and aerobic capacity are dependent on histamine signaling. Credit: Wim Derave A...
by Vanderbilt University Medical Center Yu Shyr, PhD, the Harold L. Moses Chair in Cancer Research and chair of the Department of Biostatistics at Vanderbilt University Medical Center Credit: Vanderbilt University Medical Center Immune checkpoint inhibitors have transformed cancer care to the point where the popular Cox proportional-hazards model provides misleading estimates of the treatment effect,...
by University of Pittsburgh Three-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by Tom Misteli, Ph.D., and Karen Meaburn, Ph.D. at the NIH IRP. Oncologists faced with treating older women with breast cancer often must decide if the treatment...
MASSACHUSETTS GENERAL HOSPITAL BOSTON – The anti-diabetic drug phenformin may prompt stronger cancer-fighting activities than its sister compound metformin, a finding that could have major implications for current and future clinical trials investigating both agents for their anti-cancer potential, according to researchers at Massachusetts General Hospital (MGH). In a review article in Trends in Cancer, the team presented...
NYU LANGONE HEALTH / NYU GROSSMAN SCHOOL OF MEDICINE Researchers have found a long-sought enzyme that prevents cancer by enabling the breakdown of proteins that drive cell growth, and that causes cancer when disabled. Publishing online in Nature on April 14, the new study revolves around the ability of each human cell to divide in two, with this...
by University of Exeter Credit: Public Domain A team of scientists from the University of Exeter and the University of Auckland have made a breakthrough in the quest to better understand how neural systems are able to process and store information. The researchers, including lead author Dr. Kyle Wedgwood from the University of Exeter’s Living Systems Institute,...
by Pennsylvania State University Credit: Pixabay/CC0 Public Domain Eating red meat may have a bad reputation for being bad for the heart, but new research found that lean beef may have a place in healthy diets, after all. In a randomized controlled study, researchers found that a Mediterranean diet combined with small portions of lean beef helped lower risk factors for...
by University of California, Irvine The analysis of dystrophic quadriceps by immunofluorescence microscopy highlights a novel interaction between immune cells and stromal progenitors that stimulates fibrosis during muscular dystrophy. Eosinophils are depicted in green, ILC2s in red and stromal progenitors in blue. Credit: UCI School of Medicine A new study, led by the University of California,...
