by Cecil Jack Weale, The Conversation Diabetes is a growing public health burden. Credit: Ververidis Vasilis/Shutterstock Type 2 diabetes is characterized by elevated blood glucose levels. This can cause complications that lead to damage to the kidneys, nerves, and the retina in eyes. Other complications can lead to heart diseases and diabetic foot ulcers, which eventually...
New hydrogel can repair tears in human tissue
by Valérie Geneux, Ecole Polytechnique Federale de Lausanne The gel is injected directly into the tissue. Credit: Alain Herzog 2021 EPFL EPFL scientists have developed an injectable gel that can attach to various kinds of soft internal tissues and repair tears resulting from an accident or trauma. Our soft tissues can be torn during a ski...
Researchers discover new way to monitor and prevent nerve cell deterioration after TBI
by University Hospitals Cleveland Medical Center In a new study, published online today in Cell, researchers have discovered a new way to prevent brain nerve cells from deteriorating after injury, which also revealed a potential mechanistic link between TBI and AD. Credit: University Hospitals/The Pieper Lab Violent blows or jolts to the head can cause traumatic...
Inflammation a key to targeting pregnancy-associated breast cancer
by Garvan Institute of Medical Research Microscopy image of mammary gland alveoli during lactation. Credit: Dr David Gallego-Ortega New research led by the Garvan Institute of Medical Research has revealed how breast cancer cells that develop during or after pregnancy change their environment to form more aggressive tumors. In experimental models of pregnancy associated breast cancer, researchers found that cancer cells...
Parkinson’s disease: Wearable sensors to track symptoms
by Giorgia Guglielmi, Ecole Polytechnique Federale de Lausanne Distribution of gait speed at home and the average values of the gait speed for the clinical assessments for each patient. Credit: npj Parkinson’s Disease (2021). DOI: 10.1038/s41531-021-00171-0 EPFL scientists have developed algorithms that, combined with wearable sensors, could help clinicians to monitor the progression of Parkinson’s disease and assess...
Huntington’s Disease: Neural traffic could help understand the disease
by Università di Trento In Huntington’s Disease, axonal transport is defective and this leads to neuronal degeneration. In this work, we found that the protein mutated in Huntington’s Disease, called huntingtin (HTT), needs to be methylated by the enzyme PRMT6 in order to guarantee an efficient axonal transport and the survival of neural cells (in...
Brown fat cell discovery opens new doors for obesity treatment
By Nick Lavars April 12, 2021 Brown fat cells derived from cells expressing the Trpv1 receptor, seen in green, have opened up interesting new pathways for the treatment of obesity Joslin Diabetes Center The human body carries different types of fat cells, and some of them are more desirable than others. White fat stores our...
Real-world evidence from Israel on VOCs and SARS-CoV-2 vaccine protection
By Dr. Tomislav Meštrović, MD, Ph.D. Apr 12 2021 A new study by Israeli researchers tested the hypothesis that certain SARS-CoV-2 variants of concern can overcome protection conferred by Pfizer-BioNTech (BNT162b2) mRNA vaccine and found evidence of increased breakthrough rates in vaccinated individuals. The research paper is currently available on the medRxiv*preprint server. Study: Evidence for increased breakthrough rates of SARS-CoV-2...
Busting Clots and Clearing Up A Chemical Mystery
Georgia Tech researchers discover promising new treatment for dangerous thrombosis. In a fortuitous case of mistaken chemical identity, a team of Georgia Tech bioengineers has discovered a promising new way to treat dangerous blood clots without the potentially harmful side effects of other clot-busting drugs. “It was a happy accident,” said David Ku, Regents’ professor in the George...
Technique allows mapping of epigenetic information in single cells at scale
Histones are tiny proteins that bind to DNA and hold information that can help turn on or off individual genes. Researchers at Karolinska Institutet have developed a technique that makes it possible to examine how different versions of histones bind to the genome in tens of thousands of individual cells simultaneously. The technique was applied to the...