OSAKA UNIVERSITY IMAGE: Persistent infection and, potentially, cancer development are regulated by Helicobacter pylori (H. pylori) small RNA HPnc4160: H. pylori’s small RNA HPnc4160 suppresses the expression of messenger RNAs of pathogenic factors. When H. pylori infects the gastric mucosa, a mutation is introduced into a continuous thymidine (T) sequence (T-repeat) located upstream of the gene encoding HPnc4160. Because the...
In non-alcoholic fatty liver disease, regimented exercise has beneficial effects on the liver that are unrelated to weight loss
UNIVERSITY OF TSUKUBA IMAGE: Researchers at the University of Tsukuba have shown that an exercise regimen reduces liver steatosis and stiffness in patients with non-alcoholic fatty liver disease. These gains in hepatic health are mediated through modification of inter-organ cross-talk, circulatory organokine alterations and reductions in inflammation and oxidative stress. Because these benefits are unrelated...
Another way ‘good’ cholesterol is good: combatting inflammation
by American Heart Association Credit: CC0 Public Domain Testing how well “good” cholesterol particles reduce inflammation may help predict who is at heightened risk to develop cardiovascular disease caused by narrowed arteries, according to research published today in the American Heart Association’s flagship journal Circulation. Assessing levels of high-density lipoprotein (HDL) cholesterol, known as “good cholesterol,” are already a...
Predicting mutated gene associated with melanoma
by Rae Lynn Mitchell, Texas A&M University Melanoma in skin biopsy with H&E stain — this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0 Although risk for melanoma, the most serious type of skin cancer, is often associated with ultraviolet light exposure, genetic factors are also at play, with some families being more prone...
New genetic drug target for treatment resistant colorectal cancer
by Wellcome Trust Sanger Institute Credit: Unsplash/CC0 Public Domain Targeting a specific cancer survival gene in colorectal cancer could lead to new treatment options for advanced disease, new research suggests. Researchers from the Wellcome Sanger Institute, in collaboration with the Candiolo Cancer Institute in Italy and the Netherlands Cancer Institute, used state-of-the-art patient derived organoid models to gather information about this...
Pentagon scientists reveal a microchip that senses COVID-19 in your body BEFORE you show symptoms and a filter that extracts the virus from blood
By HARRIET ALEXANDER FOR DAILYMAIL.COM PUBLISHED: 22:40 EDT, 11 April 2021 | UPDATED: 02:15 EDT, 12 April 2021 Pentagon scientists working inside a secretive unit set up at the height of the Cold War have created a microchip to be inserted under the skin, which will detect COVID-19 infection, and a revolutionary filter that can remove the virus from the blood when...
Botox sheds light on ‘inner workings’ of the brain, may unlock treatments for Parkinson’s disease
by Study FindsShare NEW YORK — Botox is best-known for its “fountain of youth” effects on an aging face, but scientists have uncovered a new use for the toxin. Researchers at New York University say Botox helps to reveal the inner workings of the brain — which could lead to treatments for Parkinson’s disease. The botulinum toxin shows...
New polypeptide could provide universal protection against coronaviruses
By Sally Robertson, B.Sc. Apr 11 2021 Researchers in the United States have developed an inhibitor of the spike protein found on the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that limits its formation in host human cells that would otherwise be the source of newly generated virions. The SARS-CoV-2 virus is the agent responsible...
Smoking cannabis significantly impairs vision, study finds
UNIVERSITY OF GRANADA IMAGE: ACCORDING TO THE NATIONAL SURVEY ON ALCOHOL, DRUGS AND OTHER ADDICTIONS IN SPAIN 2019-2020, CANNABIS USE HAS INCREASED SINCE 2011 IN SPAIN CREDIT: UNIVERSITY OF GRANADA A study carried out by the University of Granada indicates that smoking cannabis significantly alters key visual functions, such as visual acuity, contrast sensitivity, three-dimensional...
Dietary cocoa improves health of obese mice; likely has implications for humans
by Jeff Mulhollem, Pennsylvania State University This mouse was not among those that participated in the study, and the mice in the study consumed cocoa powder and not chocolate like this one is eating. However, according to lead researcher Joshua Lambert, epidemiological and human-intervention studies have suggested that chocolate consumption is associated with reduced risk of...