UNIVERSITAT POMPEU FABRA – BARCELONA IMAGE: RESEARCHERS RAFAEL MALDONADO, MARIA GALLO AND DAVID ANDREU. CREDIT: UPF An international team, led by researchers from Pompeu Fabra University (UPF) in Barcelona, Spain, David Andreu and Rafael Maldonado, has developed a peptides family that allows delta-9-tetrahydrocannabinol (THC), the main component of Cannabis sativa, to fight pain in mice without side...
Science moves closer to diet that improves metabolic health without sharp cuts in calories
PENNINGTON BIOMEDICAL RESEARCH CENTER IMAGE: METHIONINE RESTRICTION WITH OXIDIZED CASEIN IS EQUALLY EFFECTIVE AS ELEMENTAL DIET. CREDIT: PENNINGTON BIOMEDICAL RESEARCH CENTER BATON ROUGE, Louisiana – A diet that improves the biomarkers of metabolic health, and that could potentially slow the aging process, has moved a step closer to reality. “We’ve known for years that restricting the amino acid methionine...
The viruses in our genes: When activated, they damage brain development
HELMHOLTZ ZENTRUM MÜNCHEN – GERMAN RESEARCH CENTER FOR ENVIRONMENTAL HEALTH IMAGE: NEURONS ON THE RIGHT HAVE LOST THEIR FUNCTION AND SHOW A DIFFERENT PHENOTYPE. CREDIT: HELMHOLTZ ZENTRUM MÜNCHEN / MICHELLE VINCENDEAU Since our ancestors infected themselves with retroviruses millions of years ago, we have carried elements of these viruses in our genes – known as...
Study finds new and effective treatment for vitamin D deficiency
by Boston University School of Medicine Credit: Pixabay/CC0 Public Domain There are several million people worldwide with various fat malabsorption syndromes including those who have undergone gastric bypass surgery and those with obesity. These patients often have a difficult time absorbing vitamin D and both groups of patients are at an increased risk for vitamin D...
How injured nerves stop themselves from healing
by Ruhr-Universitaet-Bochum Central nervous system injuries cannot heal for a variety of reasons. Therefore, lifelong disabilities remain. Credit: RUB, Kramer Three main causes for the inability of injured nerves of the central nervous system, or CNS, to regenerate have been known to date: the insufficient activation of a regeneration program in injured nerve cells that stimulates...
Overcoming long-term trauma can be facilitated through activity in nucleus reuniens
by Ecole Polytechnique Federale de Lausanne EPFL scientist Johannes Gräff holding a model of a brain. Credit: Alain Herzog / EPFL How the brain deals with trauma is complex, and humans get over trauma differently depending on whether it happened long ago or if it was recent. But what scientific evidence do we have about the...
Immunotherapy drug can beat back early-stage lung cancer
by Dennis Thompson An immunotherapy drug is the first to significantly reduce the risk of cancer recurrence or death in people with early-stage lung cancer, researchers report. Atezolizumab reduced by 34% the risk of disease recurrence or death in a certain group of people with stage II to IIIA non-small cell lung cancer —those whose tumors carry a protein...
Blocking a protein in liver cells protects against insulin resistance, fatty liver disease
by University of California, Los Angeles Mitochondria inside liver cells (hepatocytes). Credit: Mayuko Segawa, Liesa lab at UCLA Health A new multi-institution study led by a team of researchers at the David Geffen School of Medicine demonstrated that blocking a protein called ABCB10 in liver cells protects against high blood sugar and fatty liver disease in obese mice....
Researchers identify novel approach to repair the human heart
by Loyola University Health System Credit: Pixabay/CC0 Public Domain A team of scientists from Loyola University Chicago’s Stritch School of Medicine have discovered a critical component for renewing the heart’s molecular motor, which breaks down in heart failure. Approximately 6.2 million Americans have heart failure, an often fatal condition characterized by the heart’s inability to pump enough blood...
New single-cell analysis tool links immune cells to kidney cancer recurrence
by Columbia University Irving Medical Center Credit: CC0 Public Domain The immune nature of kidney cancer stands out when compared to other cancers: More immune cells infiltrate kidney cancers than most other solid tumors, and kidney cancer is one of the most responsive malignancies to today’s immunotherapy regimens. But despite treatment, many patients with clear cell...