SAY COMMUNICATIONS LUGANO, 7 May, 2021- Findings presented at today’s EADV 2021 Spring Symposium suggest that an imbalance in gut microbiota (dysbiosis), could play a significant role in the progression of inflammatory skin disease, Hidradenitis Suppurativa (HS). HS is a painful, long-term skin condition, with a chronic and relapsing nature that significantly impacts patients’ quality...
Month: <span>May 2021</span>
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Discovery of a new genetic cause of hearing loss illuminates how inner ear works
UNIVERSITY OF PENNSYLVANIA SCHOOL OF MEDICINE PHILADELPHIA– A gene called GAS2 plays a key role in normal hearing, and its absence causes severe hearing loss, according to a study led by researchers in the Perelman School of Medicine at the University of Pennsylvania. The researchers, whose findings are published online today in Developmental Cell, discovered that the protein encoded...
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Breaching the blood-brain barrier to deliver precious payloads
GEORGIA INSTITUTE OF TECHNOLOGY IMAGE: GEORGIA TECH MECHANICAL ENGINEERING PH.D. STUDENT YUTONG GUO (LEFT) AND HER MENTOR, ASSISTANT PROFESSOR COSTAS ARVANITIS, HAVE DEVELOPED A WAY TO USE ULTRASONICS TO TREAT BRAIN DISEASE. CREDIT: ASHLEY RITCHEY, GEORGIA TECH RNA-based drugs have the potential to change the standard of care for many diseases, making personalized medicine a...
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Stem cell therapy for pelvic organ prolapse
by Hudson Institute of Medical Research Graphical abstract. Credit: Applied Materials Today (2020). DOI: 10.1016/j.apmt.2020.100890 Pelvic organ prolapse—POP—is a hidden disease. While the injury happens during childbirth, the patient may not know about the damage until many years later, often during menopause. A potential new stem cell treatment, which is being developed in the laboratory but is not yet...
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Study finds that regulatory protein prevents signaling that triggers cell death
by Leigh MacMillan, Vanderbilt University The team studying the regulation of innate immune response includes (front row, from left) Yang Zhao, Ph.D., Antiana Richardson, (back row, from left) William Dunker, Xiang Ye, Ph.D., and John Karijolich, Ph.D. Credit: Susan Urmy A protein implicated in neurodegenerative diseases including amyotrophic lateral sclerosis (ALS) prevents the activation of an...
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New research reveals why some patients may test positive for COVID-19 long after recovery
by Eva Frederick, Whitehead Institute for Biomedical Research An image of lung cancer cells infected with the SARS-CoV-2 virus. Blue represents DNA, green shows the SARS-CoV-2 nucleocapsid protein, and red represents double-stranded RNA, which occurs when the virus replicates its genome. A new study from the Jaenisch lab suggests that some virus RNA can be reverse transcribed...
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Tropical ginger treatment for blocking inflammation
by Nara Institute of Science and Technology ACA ameliorates mitochondrial damage, leading to the suppression of NLRP3-inflammasome activity and subsequent IL-1b release. Credit: Nara Institute of Science and Technology Many natural compounds have various anti-inflammatory and other beneficial properties that humans have been utilizing for medicinal purposes for hundreds of years. However, the specific molecular...
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Researchers find possible novel migraine therapy
by Lori Botterman, University of Illinois at Chicago Credit: Sasha Wolff/Wikipedia By discovering a potential new cellular mechanism for migraines, researchers may have also found a new way to treat chronic migraine. Amynah Pradhan, associate professor of psychiatry at the University of Illinois Chicago, is the senior author of the study, whose goal was to identify a new...
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New evidence links gut bacteria and neurodegenerative conditions
by University of Florida Worms colonized by a non- pathogenic control E. coli. Credit: University of Florida Neurodegenerative diseases such as Alzheimer’s, Parkinson’s and ALS affect millions of adults, but scientists still do not know what causes these diseases, which poses a significant roadblock to developing treatments or preventative measures. Recent research suggests that people with...
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Researchers develop new graphite-based sensor technology for wearable medical devices
Researchers at AMBER, the SFI Centre for Advanced Materials and BioEngineering Research, and from Trinity’s School of Physics, have developed next-generation, graphene-based sensing technology using their innovative G-Putty material. The team’s printed sensors are 50 times more sensitive than the industry standard and outperform other comparable nano-enabled sensors in an important metric seen as a game-changer in...