Month: <span>May 2021</span>

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Gene therapy in Alzheimer’s disease mouse model preserves learning and memory
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Gene therapy in Alzheimer’s disease mouse model preserves learning and memory

by Scott Lafee,  University of California – San Diego PET scan of a human brain with Alzheimer’s disease. Credit: public domain Researchers at University of California San Diego School of Medicine, with colleagues elsewhere, have used gene therapy to prevent learning and memory loss in a mouse model of Alzheimer’s disease (AD), a key step toward eventually...

New map reveals genes that control the skeleton
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New map reveals genes that control the skeleton

by  Garvan Institute of Medical Research X ray of knees. Credit: Garvan Institute of Medical Research Research led by the Garvan Institute of Medical Research has for the first time mapped the unique genetic profile of the skeleton’s ‘master regulator’ cells, known as osteocytes. The study published today in Nature Communications outlines the genes that are switched on...

Crohn’s disease patients have specific IgG antibodies to human bacterial flagellins
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Crohn’s disease patients have specific IgG antibodies to human bacterial flagellins

by Jeff Hansen,  University of Alabama at Birmingham High magnification micrograph of Crohn’s disease. Biopsy of esophagus. H&E stain. Credit: Nephron/Wikipedia Last year, Charles O. Elson, M.D., demonstrated a potential preventive treatment for Crohn’s disease, a form of inflammatory bowel disease. He used a mouse model that included immune-reactive T cells from patients with Crohn’s disease...

Researchers find obesity linked to reduced blood flow to the brain
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Researchers find obesity linked to reduced blood flow to the brain

by  Trinity College Dublin Credit: CC0 Public Domain A new study from scientists at The Irish Longitudinal Study on Aging (TILDA) at Trinity College Dublin reveals important findings, indicating that being overweight or obese significantly reduces blood flow in the brain. The study also shows that increased physical activity can positively modify, or even negate, this...

Repairing nerves requires prods of protein
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Repairing nerves requires prods of protein

by  University of Connecticut The arrows show where oligodendrocyte precursor cells (blue – all OPCs, pink- dividing OPCs) and their growth factor receptors are in contact with microglia (green) and their signaling proteins (red). Credit: Akiko Nishiyama When there’s damage in the body, our cells call for help. UConn brain researchers just found a new way cells do...

Nearly half of older millennials have at least one chronic health condition by the time they turn 40, poll suggests
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Nearly half of older millennials have at least one chronic health condition by the time they turn 40, poll suggests

By NATALIE RAHHAL U.S. HEALTH EDITOR PUBLISHED: 19:08 EDT, 4 May 2021 | UPDATED: 19:12 EDT, 4 May 2025 Nearly half of older millennials already have chronic health conditions, a new survey suggests.  Some 44 percent of people born between 1981 and 1988 have already been diagnosed with at least one chronic medical condition, according to the CNBC/Harris poll.  The...

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New graphite-based sensor technology for wearable medical devices

TRINITY COLLEGE DUBLIN Researchers at AMBER, the SFI Centre for Advanced Materials and BioEngineering Research, and from Trinity’s School of Physics, have developed next-generation, graphene-based sensing technology using their innovative G-Putty material. The team’s printed sensors are 50 times more sensitive than the industry standard and outperform other comparable nano-enabled sensors in an important metric seen as...

Your stomach may be the secret to fighting obesity
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Your stomach may be the secret to fighting obesity

by  Indiana University School of Medicine Credit: CC0 Public Domain Scientists believe a stomach-specific protein plays a major role in the progression of obesity, according to new research in Scientific Reports. The study, co-authored by an Indiana University School of Medicine researcher, could help with development of therapeutics that would help individuals struggling with achieving and...

Research team takes gene mutation detection in blood to the next level
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Research team takes gene mutation detection in blood to the next level

by  Johns Hopkins University School of Medicine New SaferSeqS technology detects rare mutations in blood in a highly efficient manner and reduces the error rate. Credit: Elizabeth Cooke Next-generation gene sequencing (NGS) technologies—in which millions of DNA molecules are simultaneously but individually analyzed—theoretically provides researchers and clinicians the ability to noninvasively identify mutations in the blood...

Harvard gene-editing tool “sneaks” DNA into cells without making cuts
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Harvard gene-editing tool “sneaks” DNA into cells without making cuts

By Michael Irving May 03, 2021 A new genetic engineering tool called Retron Library Recombineering (RLR) could be a cleaner alternative to CRISPR CRISPR-Cas9 is a revolutionary gene-editing tool, but it’s not without its downsides. Now, scientists at Harvard have demonstrated an alternative genetic engineering system called Retron Library Recombineering (RLR), which works without cutting DNA...