Penn scientists use cryo-electron microscopy to illuminate how piperlongumine works against glioblastoma. Piperlongumine, a chemical compound found in the Indian Long Pepper plant (Piper longum), is known to kill cancerous cells in many tumor types, including brain tumors. Now an international team including researchers from the Perelman School of Medicine at the University of Pennsylvania...
New research has uncovered a way SARS coronaviruses delay an immune defence against them. The coronavirus responsible for the SARS outbreak of 2003 and the one causing the current pandemic may prevent cells from responding to infection in a similar manner. They do this by making a viral protein that keeps molecules from moving through pores in...
UNIVERSITY OF CALIFORNIA – SAN FRANCISCO Pioneering neural recordings in patients with Parkinson’s disease by UC San Francisco scientists lays the groundwork for personalized brain stimulation to treat Parkinson’s and other neurological disorders. In a study published May 3rd in Nature Biotechnology, UCSF Weill Institute for Neurosciences researchers implanted novel neurostimulation devices that monitor brain activity for many...
MICHIGAN MEDICINE – UNIVERSITY OF MICHIGAN During our waking hours, the brain is receiving a near-constant influx of sensory signals of various strengths. For decades, scientists have wondered why some signals rise to the light of conscious awareness while other signals of a similar strength remain in the dark shadows of unconsciousness. What controls the...
AMERICAN INSTITUTE OF PHYSICS IMAGE: PHOTO SHOWING RELATIVE SIZE OF SPECTROMETER (LEFT) AND CELLPHONE (RIGHT AND AT THE LOWER END OF THE SPECTROMETER). CREDIT: PETER RENTZEPIS WASHINGTON, May 4, 2021 — Scientists from Texas A&M have developed an extension to an ordinary cellphone that turns it into an instrument capable of detecting chemicals, drugs, biological...
AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (A*STAR), SINGAPORE IMAGE: Eye of a patient with exfoliation syndrome. The typical white exfoliation material deposits on the surface of the lens are visible (red arrows) with the aid of a slit lamp at 16x magnification under white light. Exfoliation material may not be visible on unaided exam. CREDIT:...
UNIVERSITY OF WÜRZBURG IMAGE: Microscopic picture of a CD8+ T cell in the CNS of a two-year-old mouse. The cytotoxic T cell (red labelling) is located in immediate proximity to a damaged nerve fiber (green labelling) and is, according to the described results, involved in its damage. The cell nuclei of all cell bodies in...
UNIVERSITY OF BRISTOL IMAGE: CUTTLEFISH CREDIT: PROF SHELBY TEMPLE University of Bristol research into octopus vision has led to a quick and easy test that helps optometrists identify people who are at greater risk of macular degeneration, the leading cause of incurable sight loss. The basis for this breakthrough was published in the latest issue of the Journal...
DUKE UNIVERSITY MEDICAL CENTER DURHAM, N.C. – When patients complain of coughing, runny nose, sneezing and fever, doctors are often stumped because they have no fundamental tool to identify the source of the respiratory symptoms and guide appropriate treatments. That tool might finally be on its way. In a study proving feasibility, researchers at Duke Health showed...
UNIVERSITY OF SOUTH FLORIDA (USF HEALTH) IMAGE: SHIXIE JIANG, MD, A THIRD-YEAR PSYCHIATRY RESIDENT AT THE USF HEALTH MORSANI COLLEGE OF MEDICINE, WAS THE LEAD AUTHOR FOR A STUDY USING AN EMERGING FUNCTIONAL NEUROIMAGING TECHNOLOGY, CALLED DIFFUSE OPTICAL TOMOGRAPHY, DURING REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION. ( rTMS). CREDIT: USF HEALTH/UNIVERSITY OF SOUTH FLORIDA TAMPA, Fla. (May...
