by University of California – San Diego Human enzyme METTL3 adds methyl groups to introduce m6A in SARS-CoV-2’s RNA. That modification prevents the virus’ RNA from triggering inflammatory molecules known as cytokines. METTL3 also leads to increased expression of pro-viral genes — those that encode proteins needed for SARS-CoV-2 replication and survival. Credit: University of California...
by Max Planck Society Credit: Unsplash/CC0 Public Domain Human decision-making depends on the flexible processing of complex information, but how the brain may adapt processing to momentary task demands has remained unclear. In a new article published in the journal Nature Communications, researchers from the Max Planck Institute for Human Development have now outlined several crucial neural processes revealing...
April 28, 2021 11:12 AM EDT Updated 11:44 AM Discovery PureTech turns 200-year-old discovery into a new approach to Alzheimer’s, while clinging to controversial amyloid hypothesis Before MRIs or CT scans, 18th-century anatomist Paolo Mascagni injected his cadavers with mercury. Ever mobile, the mercury coursed through their veins like blood, illuminating the body’s rivers and...
A team of engineering researchers at the Georgia Institute of Technology hopes to uncover new ways to diagnose and treat brain ailments, from tumors and stroke to Parkinson’s disease, leveraging vibrations and ultrasound waves. The five-year, $2 million National Science Foundation (NSF) project initiated in 2019 already has resulted in several published journal articles that...
New research from the University of Virginia School of Medicine has shed light on the No. 1 cause of epilepsy deaths, suggesting a long-sought answer for why some patients die unexpectedly following an epileptic seizure. The researchers found that a certain type of seizure is associated with sudden death in a mouse model of epilepsy and that death occurred only when...
UNIVERSITY OF VIRGINIA HEALTH SYSTEM IMAGE: ADAM GOLDFARB, MD, OF THE UNIVERSITY OF VIRGINIA SCHOOL OF MEDICINE, AND HIS COLLABORATORS HAVE MADE A DISCOVERY THAT COULD LEAD TO MORE EFFECTIVE TREATMENTS FOR ANEMIAS CAUSED BY CHRONIC INFLAMMATION. CREDIT: UVA HEALTH A combination of inexpensive oral medications may be able to treat fatigue-inducing anemias caused by...
RADIOLOGICAL SOCIETY OF NORTH AMERICA IMAGE: OVERVIEW OF THE SCAPHOID FRACTURE DETECTION PIPELINE, WHICH CONSISTED OF A SEGMENTATION AND DETECTION CONVOLUTIONAL NEURAL NETWORK (CNN). A CLASS ACTIVATION MAP IS CALCULATED AND VISUALIZED AS A HEATMAP FOR FRACTURE LOCALIZATION. CREDIT: RADIOLOGICAL SOCIETY OF NORTH AMERICA OAK BROOK, Ill. – An automated system that uses artificial intelligence...
NIH/NATIONAL INSTITUTE ON AGING IMAGE: STUDY OF MOUSE BRAIN SHOWS THE MENINGEAL LYMPHATICS SYSTEM (PURPLE AND PINK) COULD HELP REDUCE AMYLOID. CREDIT: IMAGE COURTESY OF SANDRO DA MESQUITA. Enhancing the brain’s lymphatic system when administering immunotherapies may lead to better clinical outcomes for Alzheimer’s disease patients, according to a new study in mice. Results published...
WELLCOME TRUST SANGER INSTITUTE For the first time, scientists are able to study changes in the DNA of any human tissue, following the resolution of long-standing technical challenges by scientists at the Wellcome Sanger Institute. The new method, called nanorate sequencing (NanoSeq), makes it possible to study how genetic changes occur in human tissues with...
JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY IMAGE: A PARALLEL LSTM NETWORK TAKES IN MMCG FEATURES WITH DIFFERENT RESOLUTIONS AND YIELDS OUTPUTS THAT ARE CONCATENATED TOGETHER AND THEN SENT TO A MERGING LSTM LAYER AND A DENSE LAYER TO YIELD THE VALENCE (V) AND AROUSAL (A) SEQUENCES. CREDIT: MASASHI UNOKI Ishikawa, Japan – Human beings have...
