Month: <span>June 2021</span>

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Early diagnostic and prognostic biomarkers of traumatic brain injury
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Early diagnostic and prognostic biomarkers of traumatic brain injury

by  University of Eastern Finland Credit: Unsplash/CC0 Public Domain Acute elevation in certain plasma microRNAs (miRNAs), along with downregulation of the clusterin protein within two days post-injury can act as early diagnostic and prognostic biomarkers for traumatic brain injury, according to the doctoral dissertation of Shalini Das Gupta, MSc. Traumatic brain injury (TBI) occurs when an...

Nerve stimulation effective in patients with untreatable cluster headaches
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Nerve stimulation effective in patients with untreatable cluster headaches

by  Leiden University Credit: Pavel Danilyuk via Pexels Extremely painful chronic cluster headaches—sometimes referred to as ‘suicide headaches’ – can be prevented by stimulating the occipital nerve in the back of the head, according to research conducted by Professor Emeritus of Neurology Michel Ferrari from Leiden University Medical Center (LUMC). The study showed that nerve stimulation...

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Analysis reveals origins of a leukemia that straddles diagnostic categories

by  St. Jude Children’s Research Hospital First authors Lindsey Montefiori, Ph.D., (foreground) and Xiaolong Chen, Ph.D., helped identify gene alterations that drive subsets of acute leukemias in children and adults in a joint study with Munich Leukemia Laboratory. Credit: St. Jude Children’s Research Hospital Researchers have identified gene alterations that drive a subset of acute leukemias...

Climate change lengthening allergy season
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Climate change lengthening allergy season

by Erin Digitale,  Stanford University Stanford researchers have found that changes in temperature and rainfall have lengthened allergy season in the Bay Area. Credit: Elizaveta Galitckaia/Shutterstock Air levels of pollen and mold spores in the San Francisco Bay Area are elevated for about two more months per year than in past decades, and higher temperatures are...

Common blood pressure pills could slow memory decline in over-50s, researchers say
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Common blood pressure pills could slow memory decline in over-50s, researchers say

By RYAN MORRISON FOR MAILONLINE  PUBLISHED: 09:17 EDT, 21 June 2021 | UPDATED: 09:18 EDT, 21 June 2021 Older people taking certain types of blood pressure-lowering medication had better rates of memory recall, suggesting it could be used to slow memory decline.     Researchers found that treating people over the age of 50 with angiotensin II receptor blockers, such as candesartan...

Toxicity of protein involved in Alzheimer’s triggered by a chemical ‘switch’
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Toxicity of protein involved in Alzheimer’s triggered by a chemical ‘switch’

TOKYO METROPOLITAN UNIVERSITY IMAGE: Tau proteins with cysteine groups bearing thiol groups (S) undergo chemical changes under oxidative stress to form disulfide bonds, making a toxic mutant of the tau protein that can aggregate. These go on to cause neural degeneration. Antioxidants can help reduce these back to thiols; these normal tau proteins can then...

Further hope for BCG vaccine in stemming type 1 diabetes
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Further hope for BCG vaccine in stemming type 1 diabetes

by  Massachusetts General Hospital Credit: Pixabay/CC0 Public Domain At the recent 2021 Annual Scientific Sessions of the American Diabetes Association, researchers from Massachusetts General Hospital (MGH) presented positive updates on their trials of the bacillus Calmette-Guérin (BCG) vaccine to safely and significantly lower blood sugars. In type 1 diabetes, an autoimmune disease that currently has no cure, T...

Researchers study potential new CAR-T cell therapy for multiple myeloma
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Researchers study potential new CAR-T cell therapy for multiple myeloma

by  Mayo Clinic Micrograph of a plasmacytoma, the histologic correlate of multiple myeloma. H&E stain. Credit: Wikipedia/CC BY-SA 3.0 Researchers at Mayo Clinic Cancer Center are studying a potential new chimeric antigen receptor-T cell therapy (CAR-T cell therapy) treatment for multiple myeloma. Their findings were published on Friday, June 24, in The Lancet. “CAR-T cell therapy is a type of...

Sleeper cells: Newly discovered stem cell resting phase could put brain tumors to sleep
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Sleeper cells: Newly discovered stem cell resting phase could put brain tumors to sleep

by  Arizona State University By analyzing brain stem cell data, Assistant Professor Christopher Plaisier and biomedical engineering doctoral student Samantha O’Connor saw the phases of the cell cycle mapped out in more detail than previously possible — the G0 resting phases, including a new, separate phase they called Neural G0, in addition to growth phases G1...

Muscle’s smallest building blocks disappear after stroke
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Muscle’s smallest building blocks disappear after stroke

by  Northwestern University Muscle sarcomeres (consecutive green lines), the smallest functional unit of muscle, from inside a living human. Credit: Northwestern University After suffering a stroke, patients often are unable to use the arm on their affected side. Sometimes, they end up holding it close to their body, with the elbow flexed. In a new study,...