by Allessandra Dicorato, Broad Institute of MIT and Harvard Credit: Susanna Hamilton, Broad Communications New research suggests age-related changes in blood cell chromosomes are a marker of impaired immunity. A person’s risk of severe infections increases dramatically as they grow older, but scientists do not yet understand how age might be linked to weakened immunity. Now, research shows...
Health benefits of low protein-high carbohydrate diets depend on carb type
by University of Sydney Image of a fork.Credit: Sourced from Pexels. Researchers at the University of Sydney’s Charles Perkins Centre have conducted the largest-ever study of nutrient interactions by examining the health of mice on 33 different diets containing various combinations of protein to carbs, and different sources of carbohydrate. They found that a low-protein (10% of...
A breakthrough in the physics of blood clotting
by Georgia Institute of Technology First author Yueyi Sun inside Georgia Tech’s Complex Fluids Modeling and Simulation lab, where she compares the experimental and simulated platelet-driven fibrin clot contraction process. Credit: Alexander Alexeev, Georgia Tech Heart attacks and strokes—the leading causes of death in human beings—are fundamentally blood clots of the heart and brain. Better understanding...
Researchers discover how cowpea mosaic plant virus activates immune system against cancer
by Dartmouth-Hitchcock Medical Center Though it does not infect mammals, the Cowpea mosaic plant virus is recognized by and strongly stimulates the immune system to attack and often eliminates cancerous tumors. Credit: UCSD Cowpea mosaic virus, when injected into cancerous tumors, stimulates the immune system to attack and often eliminates the tumor. In a new study,...
Odds of sperm stem cell transplant restoring fertility are as random as a coin toss—until now
by Hiroshima University After looking at the fate of transplanted spermatogonial stem cells up-close at single-cell resolution, the researchers discovered that only a small fraction repopulates as working spermatogonia. They developed a new strategy that introduces a chemical inhibitor to increase the odds of sperm stem cells choosing a fate of self-renewal. Credit: Pexels The ability...
Research advances one step closer to stem cell therapy for type 1 diabetes
by Salk Institute Functional beta cells made from human pluripotent stem cells. Insulin (red) and NKX6.1 (green) indicate two proteins produced by beta cells. Credit: Salk Institute Type 1 diabetes, which arises when the pancreas doesn’t create enough insulin to control levels of glucose in the blood, is a disease that currently has no cure...
Unexpected discovery opens a new way to regulate blood pressure
by University of Vermont An isolated cerebral arteriole from a mouse model, marked by a live-cell dye. Credit: Osama Harraz, Ph.D., University of Vermont Larner College of Medicine High blood pressure, or hypertension, is the leading modifiable risk factor for cardiovascular diseases and premature death worldwide. And key to treating patients with conditions ranging from chest...
Monoclonal antibody prevents HIV infection in monkeys, study finds
by Franny White, Oregon Health & Science University HIV-1 Virus. Credit: J Roberto Trujillo/Wikipedia An experimental, lab-made antibody can completely prevent nonhuman primates from being infected with the monkey form of HIV, new research published in Nature Communications shows. The results will inform a future human clinical trial evaluating leronlimab as potential pre-exposure prophylaxis, or PrEP,...
Largest-ever pre-adolescent brain activation study reveals cognitive function maps
by University of Vermont Credit: Pixabay/CC0 Public Domain Youth brain activation data from the largest longitudinal neuroimaging study to date provides valuable new information on the cognitive processes and brain systems that underlie adolescent development and might contribute to mental and physical health challenges in adulthood. The study published today online in Nature Neuroscience. Because of the...
Procedure using ultrasound energy found to treat high blood pressure
QUEEN MARY UNIVERSITY OF LONDON A minimally-invasive procedure that targets the nerves near the kidney has been found to significantly reduce blood pressure in hypertension patients, according to the results of a global multicentre clinical trial led in the UK by researchers at Queen Mary University of London and Barts Health NHS Trust. The study,...