by CHeBA Credit: CC0 Public Domain Latest research from UNSW Sydney’s Center for Healthy Brain Aging (CHeBA) has uncovered new insight into the underlying mechanisms of Alzheimer’s disease. The findings, published in Translational Psychiatry, examined differences between the plasma lipidome of people with Alzheimer’s disease and ‘healthy’ individuals of the same age from CHeBA’s Sydney Memory and Aging...
by Singapore-Mit Alliance For Research and Technology, Singapore-MIT Alliance for Research and Technology The figure shows the schematic illustration of RADICA. After DNA/RNA extraction, samples can be used for the detection and quantification of various targets. RPA-Cas12a reaction in each positive partition exponentially amplifies the target DNA, triggering more Cas12a activation and increasing the fluorescence readout....
by Osaka University Figure 1. (Left panel) Flow chart demonstrating dendritic cells (DCs) in wildtype (WT) and DC-specific Lamtor1-KO mice. In the absence of Lamtor1, skin-draining lymph nodes showed reduced numbers of migratory DCs. (Right panel) Representative images of the skin of WT and Lamtor1-KO mice. In the absence of Lamtor1, the contact dermatitis was impaired...
While previous research early in the pandemic suggested that vitamin D cuts the risk of contracting COVID-19, a new study from McGill University finds there is no genetic evidence that the vitamin works as a protective measure against the coronavirus. “Vitamin D supplementation as a public health measure to improve outcomes is not supported by this study....
ERA-EDTA SGLT2 inhibitors (gliflozins) were developed as oral antidiabetics. They enhance urinary glucose excretion by inhibiting SGLT-2 (sodium-dependent glucose co-transporter-2) in the renal tubuli. The discovery of kidney benefits beyond the lowering of blood sugar has been made by Professor Christoph Wanner from Germany: The EMPA-REG OUTCOME study [2] initially showed that the rate of...
AMERICAN HEART ASSOCIATION Research Highlights: Rates of Kawasaki disease – a condition that creates inflammation in blood vessels in the heart and is more common in children of Asian/Pacific Island descent – have substantially decreased in South Korea during the COVID-19 pandemic. The decrease could be due to mask-wearing, hand-washing, school closures and physical distancing, suggesting...
RMIT UNIVERSITY IMAGE: VIETNAMESE FERMENTED PORK SNACK, NEM CHUA. CREDIT: RMIT UNIVERSITY A traditional Vietnamese meat snack could hold the key to developing a safe and natural food preservative, addressing the twin global problems of food waste and food-borne illnesses. Key Points Bacteria-killing compound discovered in Nem Chua, a fermented pork snack Toxic to bacteria...
ETH ZURICH IMAGE: THIS IS HOW THE GREEN LIGHT-REGULATED GENE NETWORK WORKS CREDIT: ETH ZURICH Many modern fitness trackers and smartwatches feature integrated LEDs. The green light emitted, whether continuous or pulsed, penetrates the skin and can be used to measure the wearer’s heart rate during physical activity or while at rest. These watches have...
ERA-EDTA Focal segmental glomerulosclerosis (FSGS) is a rare form of kidney inflammation (glomerulonephritis) in which the glomeruli become increasingly scarred (sclerotic), leading to progressive loss of kidney function. Dysregulation of the immune system plays a role in pathogenesis, which is why immunosuppressive therapy with glucocorticoids can be successful, alongside supportive therapy (especially blocking of the...
TEL-AVIV UNIVERSITY IMAGE: ELONGATION OF BACTERIA DUE TO INHIBITION OF DIVISION IS CAUSED BY THE BACTERIOPHAGE PROTEIN CREDIT: DR. TRIDIB MAHATA. The battle against antibiotic-resistant bacteria: A new study at Tel Aviv University revealed a mechanism through which “good” viruses can attack the systems of “bad” bacteria, destroy them and block their reproduction. The researchers...
