Project to classify nuclei across the tree of life discovers how to transmute them from one type into another. One hundred fifty years ago, Dmitri Mendeleev created the periodic table, a system for classifying atoms based on the properties of their nuclei. This week, a team of biologists studying the tree of life has unveiled...
Sleep-Related Breathing Disorders
We all need sleep to properly function and live. Not getting enough sleep harms our well-being, health, and immunity. Even one sleepless night can affect our bodies. Today’s times do not have a positive effect on proper sleep and its sufficient amount. Work-related stress, irregular lifestyle, overwhelming responsibilities, or mental health problems do not help....
Pfizer jab less effective, still protects against Indian strain: study
Credit: Pixabay/CC0 Public Domain The Pfizer vaccine is slightly less effective but appears to still protect against the more transmissible Indian strain of the virus that causes COVID-19, according to a study by France’s Pasteur Institute. “Despite slightly diminished efficacy, the Pfizer vaccine probably protects” against the Indian variant, according to laboratory test results, said...
Ethnic diversity helps identify more genomic regions linked to diabetes-related traits
by University of Exeter Credit: CC0 Public Domain By including multi-ethnic participants, a large-scale genetic study has identified more regions of the genome linked to type 2 diabetes-related traits than if the research had been conducted in Europeans alone. The international MAGIC collaboration, made up of more than 400 global academics, conducted a genome-wide association meta-analysis led...
Scientists discover a new genetic form of ALS in children
by National Institutes of Health NIH researchers discovered a new form of ALS that begins in childhood. The study linked the disease to a gene called SPLTC1. As part of the study, NIH senior scientist Carsten Bonnemann, M.D., (right) examined Claudia Digregorio (left), a patient from the Apulia region of Italy. Credit: NIH/NINDS. In a study...
Vaccines charge up natural immunity against SARS-CoV-2
by Rockefeller University Plasma ELISAs and neutralizing activity. a-b, Plasma IgG antibody binding to SARS-CoV-2 RBD (a) and N protein (b), and plasma neutralizing activity (c–e) 12 months after infection (N=63). a and b, ELISA curves from non-vaccinated (black lines) individuals, as well as individuals who received one or two doses of a COVID-19 mRNA vaccine...
A New Type Of COVID-19 Vaccine Could Debut Soon
June 6, 20216:02 AM ET JOE PALCA A vial of the experimental Novavax coronavirus vaccine is ready for use in a London study in 2020. Novavax’s vaccine candidate contains a noninfectious bit of the virus — the spike protein — with a substance called an adjuvant added that helps the body generate a strong immune...
How do bad kidneys lead to heart disease? Broken cellular clocks provide new clues
KYUSHU UNIVERSITY IMAGE: CKD-INDUCED METABOLIC DYSFUNCTION OF VITAMIN A IN THE LIVER ELEVATES LEVELS OF VITAMIN A IN THE BLOOD. THE ELEVATION INDUCES UPREGULATION OF GPR68 IN MONOCYTES VIA COCK GENES. THE UPREGULATION CREDIT: OHDO LAB/KYUSHU UNIVERSITY Fukuoka, Japan–According to the Global Burden of Disease Study 2017, close to nine percent of the global population...
Self-excising designer proteins report isoform expression
HELMHOLTZ ZENTRUM MÜNCHEN – GERMAN RESEARCH CENTER FOR ENVIRONMENTAL HEALTH IMAGE: SELF-EXCISING DESIGNER PROTEINS REPORT ISOFORM EXPRESSION. CREDIT: BARTH VAN ROSSUM Proteins are the key players in our cellular processes. Their generation follows principles called transcription and translation. First, DNA copies its genetic information to messenger RNA (mRNA), which then determines the sequence in a...
Giving brown fat a boost to fight type 2 diabetes
UT SOUTHWESTERN MEDICAL CENTER IMAGE: WITH EXTRA PLIN5, MITOCHONDRIA IN BROWN FAT CELLS BOOST THEIR CAPACITY TO BURN FAT EVEN AT ROOM TEMPERATURE. CREDIT: DRS. VIOLETA I. GALLARDO-MONTEJANO AND PERRY E. BICKEL. DALLAS – June 4, 2021 – Increasing a protein concentrated in brown fat appears to lower blood sugar, promote insulin sensitivity, and protect...