by Mike Williams, Rice University Scientists at Rice University and Baylor College of Medicine are using pClick conjugation to create therapeutic antibodies that target bone cancers. The conjugate incorporates bisphosphonate molecules that bind to the bone hydroxyapatite matrix. Credit: Baylor College of Medicine/Rice University Bone cancer is hard to treat and prone to metastasis. Research teams...
by University of Texas Health Science Center at San Antonio Credit: CC0 Public Domain A typical Western high-fat diet can increase the risk of painful disorders common in people with conditions such as diabetes or obesity, according to a groundbreaking paper authored by a team led by The University of Texas Health Science Center at San...
Hypercapnia is a build-up of carbon dioxide (CO2) in the blood. It occurs when tiny air sacs in the lungs called alveoli are unable to adequately exchange CO2 from the blood for oxygen. This form of respiratory failure can come on suddenly, with causes such as infection or an opioid overdose, and is particularly dangerous,...
COLUMBIA UNIVERSITY IRVING MEDICAL CENTER Legend has it that Marie Antoinette’s hair turned gray overnight just before her beheading in 1791. Though the legend is inaccurate–hair that has already grown out of the follicle does not change color–a new study from researchers at Columbia University Vagelos College of Physicians and Surgeons is the first to offer quantitative...
THE OBESITY SOCIETY SILVER SPRING, Md.– Although Americans spend billions on them, published research shows a lack of strong evidence that dietary supplements and alternative therapies help adults lose weight, according to a new study published in Obesity, the flagship journal of The Obesity Society (TOS). There are hundreds of weight-loss supplements like green tea extract, chitosan, guar...
NYU LANGONE HEALTH / NYU GROSSMAN SCHOOL OF MEDICINE Researchers rescued mice from early death caused by a muscle-weakening disease, not by correcting the flawed gene that causes it, but instead by targeting another protein in the same signaling pathway. Led by NYU Grossman School of Medicine researchers, a new study found that an antibody treatment not...
WILEY In a study published in the Journal of Bone and Mineral Research, investigators developed and validated a genetic risk score for predicting the onset and severity of the most common type of scoliosis in adolescents–called adolescent idiopathic scoliosis (AIS). AIS causes spinal deformities in as many as 3% of youth, and because its heritability is high,...
UNC LINEBERGER COMPREHENSIVE CANCER CENTER IMAGE: “Because similar gene fusions have been observed in other malignancies, the mechanism we elucidated could explain other types of cancer as well,” said UNC Lineberger’s Douglas H. Phanstiel, Ph.D. “We believe that our research could open up new and innovative avenues to attack cancer cells.” CREDIT: UNIVERSITY OF NORTH...
by Baylor College of Medicine Modifying the activity of gene Rap1 in VMH neurons of the hypothalamus can regulate blood glucose in an animal model. Credit: M. Fukuda/JCI insight, 2021 Managing type 2 diabetes typically involves losing weight, exercise, and medication, but new research by Dr. Makoto Fukuda and colleagues at Baylor College of Medicine and...
by Medical University of South Carolina Hollings Cancer Center researcher Nancy Klauber-DeMore, M.D., is leading the first breakthrough in pediatric osteosarcoma treatment in decades. Credit: MUSC Hollings Cancer Center/Marquel Coaxum In cancer that has not seen new targeted therapies for over 20 years, MUSC Hollings Cancer Center researcher and oncologist Nancy Klauber-DeMore, M.D., is pioneering new...
