by University of Maryland School of Medicine Healthy mouse retinas (top) with support cells (outlined in blue) and photoreceptors (purple). In the CIB2 mutant mouse retina (bottom), the photoreceptors are not digested as fast and accumulate. Credit: Saumil Sethna With the National Eye Institute reporting that about 11 million older adults in the U.S. endure a...
Cellular signatures of kidney tumors discovered
by Wellcome Trust Sanger Institute Credit: CC0 Public Domain The origins of seven types of kidney cancer, including several rare subtypes, have been identified by researchers at the Wellcome Sanger Institute, Great Ormond Street Hospital (GOSH), the Princess Máxima Center for Pediatric Oncology, and Oncode Institute. The findings confirm that these cancers have their origin in...
Potential noninvasive treatment for Alzheimer’s disease
by University of Queensland Credit: University of Queensland Ultrasound can overcome some of the detrimental effects of aging and dementia without the need to cross the blood-brain barrier, researchers at The University of Queensland have found. Professor Jürgen Götz from UQ’s Queensland Brain Institute (QBI) led a multidisciplinary team who showed low-intensity ultrasound effectively restored cognition without opening the barrier...
If the right hand is hypersensitive due to an injury to the left
by Ruhr-Universitaet-Bochum Credit: Unsplash/CC0 Public Domain Peripheral nerves refer to nerves that lie outside of the brain and spinal cord. They run throughout the entire body. These bundles of nerve fibers can be damaged in the event of blunt or sharp force trauma due to accidents, as well as during surgery. Injuries to the peripheral nerves...
Inflammatory proteins may slow cognitive decline in aging adults
by Massachusetts General Hospital PET scan of a human brain with Alzheimer’s disease. Credit: public domain Research has previously linked inflammation to Alzheimer’s disease (AD), yet scientists from Massachusetts General Hospital (MGH) and the Harvard Aging Brain Study (HABS) have made a surprising discovery about that relationship. In a new study published in Alzheimer’s & Dementia: The Journal...
Autopsy study shows how COVID harms the brain
The brains of people who died from COVID-19 were remarkably similar to the brains of people who die from neurodegenerative diseases such as Alzheimer’s and Parkinson’s, showing inflammation and disrupted circuitry, researchers report. “The brains of patients who died from severe COVID-19 showed profound molecular markers of inflammation, even though those patients didn’t have any reported clinical...
Secretin hormone induces satiation by activating brown fat
by University of Turku Positron emission tomography images showing glucose tracer uptake after placebo and secretin infusions. Arrows show the location of brown adipose tissue. Credit: University of Turku Researchers from the Turku PET Centre and the Technical University of Munich have discovered a new mechanism controlling satiation. According to the recently published study, the hormone...
Experimental brain implant instantly detects and relieves pain
By Rich Haridy June 21, 2021 New research is a very early step towards a brain implant that can detect and suppress pain in real timeadamfaheydesigns/Depositphotos Researchers from the New York University School of Medicine have developed a brain implant designed to detect pain sensations in real-time and deliver bursts of pain-relieving stimulation. The device is...
Bottling the smell of happiness to help treat depression
It may sound like something out of a fantasy movie, but scientists hope to be able to bottle the smell of happiness so it can be used to help people with phobias or depression. Image credit: Pixabay (Free Pixabay license) Our bodies produce different scents when we feel happy or afraid. These so-called chemosignals –...
Targeted Therapy for ‘Undruggable’ Lung Cancer Stems from Decades of UCSF Research
Over the past two decades, targeted cancer therapies have changed the prognosis for thousands of patients. By targeting the specific genetic mutation behind a patient’s cancer, these therapies have enabled increasing numbers of patients to experience fewer toxic side effects and, often, live free of disease following their treatment. But until May 28, 2021, when...