Leukemia stem cells are rare cells that can renew themselves while continuing to generate malignant cells known as leukemic blasts. These cells are difficult to eradicate using chemotherapy drugs and frequently lead to the recurrence of leukemia. Leukemia stem cells, however, are dependent on a protein complex called polycomb repressive complex 1, or PRC1, which...
UNIVERSITY OF CAMBRIDGE Researchers have shown why people with mental health disorders, including anorexia and panic disorders, experience physical signals differently. The researchers, from the University of Cambridge, found that the part of the brain which interprets physical signals from the body behaves differently in people with a range of mental health disorders, suggesting that it could...
THE MOUNT SINAI HOSPITAL / MOUNT SINAI SCHOOL OF MEDICINE New York, NY (June 22, 2021) – A new class of drugs that inhibits a “master switch” involved in the vast majority of cases of mantle cell lymphoma (MCL), a fatal subtype of non-Hodgkin’s lymphoma, has been discovered by researchers at Mount Sinai. In a study in Clinical...
KECK SCHOOL OF MEDICINE OF USC IMAGE: JOSEPH WIEMELS, Ph.D., CANCER EPIDEMIOLOGY PROGRAM AT THE USC NORRIS COMPREHENSIVE CANCER CENTER CREDIT: RICHARD CARRASCO Increased risk of cancer due to a genetic predisposition in first- and second-degree relatives is long-established but has previously only been studied in white or European populations. Now, a new study published...
UNIVERSITÉ DE GENÈVE IMAGE: SURFACE ARCHITECTURE OF A PSEUDOMONAS AERUGINOSA COLONY GROWN FOR THREE DAYS ON SEMI-SOLID MEDIUM (STEREOMICROSCOPE, ARTIFICIAL COLOR). CREDIT: © UNIGE Pseudomonas aeruginosa is an opportunistic pathogenic bacterium present in many ecological niches, such as plant roots, stagnant water, or even the pipes of our homes. Naturally very versatile, it can cause...
by Frontiers Credit: CC0 Public Domain Post-traumatic stress disorder (PTSD) and migraine often co-occur, but researchers knew relatively little about how or why this happens. A new study in Frontiers in Neuroscience is the first to investigate if the conditions have a common genetic basis. By studying identical twins, where one twin in each pair lives...
by Cedric Ricks, University of Cincinnati Kaitlin Hart, a UC doctoral student, and Thomas Thompson, Ph.D., shown in a laboratory in the UC College of Medicine. Credit: Colleen Kelley/UC Creative + Brand. Researchers at the University of Cincinnati College of Medicine have developed a blueprint for a protein that plays an important role in the development and...
by Anne M Stark, Lawrence Livermore National Laboratory Gene expression in mouse knee joint chondrocytes was analyzed using single-cell RNA sequencing, which identified nine chondrocyte subpopulations with distinct molecular profiles. Credit: Lawrence Livermore National Laboratory Articular cartilage is a connective tissue lining the surfaces of joints. When the cartilage severely wears down, it leads to osteoarthritis...
by University of California, Irvine T regulatory cells (green with red nuclei) interact with antigen-presenting cells (magenta) in a tumor (blue). The Treg cell on top is activated (green fluorescence in the nucleus), while the one at the bottom is not (green fluorescence outside the nucleus). Activation of Treg cells promotes tumor growth. Credit: Francesco Marangoni...
by Karolinska Institutet Credit: CC0 Public Domain Early intervention for disruptive behavior disorders in children reduces the risk of antisocial development and psychiatric problems later in life. Parental training and child CBT are two interventions about which more needs to be known concerning the effects on disruptive behavior disorders. According to a new doctoral thesis from...
