by University of Otago Credit: University of Otago University of Otago and UK researchers have developed a world-first weight-loss device to help fight the global obesity epidemic. DentalSlim Diet Control is an intra-oral device fitted by a dental professional to the upper and lower back teeth. It uses magnetic devices with unique custom-manufactured locking bolts. It allows the wearer to...
Covid-19 patients recover faster with metabolic activator treatment, study shows
by KTH Royal Institute of Technology The cocktail of metabolic activators was reported to reduce recovery time for COVID-19 patients. Credit: KTH Royal Institute of Technology Metabolic activators can reduce recovery time by as many as 3.5 days in patients with mild-to-moderate COVID-19, according to a study published today in Advanced Science. The researchers also found that treatment with...
Sunflower peptide as template for potential analgesic
by Medical University of Vienna Credit: CC0 Public Domain A naturally occurring peptide in sunflower seeds was synthetically optimized and has now been identified as a potential drug for treating abdominal pain or inflammation (in the gastrointestinal tract, abdominal area, and/or internal organs). That is the finding of an international study led by Christian Gruber from...
Study explores how the perception of internal bodily signals influences the concept of self
by Ingrid Fadelli, Medical Xpress Interoceptive constraints on each dimension of the concept of self. The colored arrows show the known influences of specific interoceptive signals on specific facets of the self-concept. Truncated lines with no terminal arrow indicate hypothetical links between interoception and self-concept that are yet to be investigated. Credit: Monti et al....
Lambda lineage of SARS-CoV-2 has potential to become variant of concern
By Sally Robertson, B.Sc. Jun 27, 2021 Researchers have described the first reported infection with the C.37 (Lambda) lineage of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Southern Brazil. The SARS-CoV-2 virus is the agent responsible for the ongoing coronavirus disease 2019 (COVID-19) pandemic. The Lambda lineage was classified as a variant of interest (VOI)...
New approach to treat inflammatory disorders while preserving protection against opportunistic infections
Researchers at Case Western Reserve University have discovered a new technique to control inflammatory disorders that also maintains a patient’s ability to fight off infections. Principal investigator Carlos Subauste, professor of medicine and pathology at the Case Western Reserve School of Medicine, and his team have identified the interaction of particular proteins as a therapeutic target...
Inflatable Neurostimulator for Minimally Invasive Pain Control
JUNE 28TH, 2021 CONN HASTINGS Researchers at the University of Cambridge created a spinal stimulation device that can help to control severe pain. Unlike existing technologies, which require invasive surgery for implantation, the new device can be delivered using a needle. Once implanted, the device unfurls and inflates in place to provide extensive coverage during spinal cord...
Heart failure is associated with an increased risk of cancer
EUROPEAN SOCIETY OF CARDIOLOGY Sophia Antipolis – 28 June 2021: A study in more than 200,000 individuals has found that patients with heart failure are more likely to develop cancer compared to their peers without heart failure. The research is presented today at Heart Failure 2021, an online scientific congress of the European Society of Cardiology (ESC),1...
Oncotarget: Glucocorticoid receptor antagonism promotes apoptosis in solid tumor cells
IMPACT JOURNALS LLC IMAGE: Relacorilant improves the efficacy and promotes the apoptotic activity of cytotoxic therapy in xenograft models under physiological cortisol conditions. (A) In the MIA PaCa-2 model, the efficacy of the combination of paclitaxel + relacorilant was significantly better than paclitaxel alone (non-parametric T-test P < 0.0001). (B) In the MIA PaCa-2 model,...
Scientists at UC say restoring a brain protein, not removing amyloid plaques, should be the target of Alzheimer’s dementia therapies
UNIVERSITY OF CINCINNATI IMAGE: ALBERTO ESPAY, MD, MSC, PROFESSOR OF NEUROLOGY AT THE UC COLLEGE OF MEDICINE AND DIRECTOR AND ENDOWED CHAIR OF THE JAMES J. AND JOAN A. GARDNER FAMILY CENTER FOR PARKINSON’S DISEASE AND MOVEMENT DISORDERS. CREDIT: COLLEEN KELLEY/UC BRAND + CREATIVE Experts estimate more than 6 million Americans are living with Alzheimer’s...