by University of Gothenburg Immune profiles of pre- and post-treatment (one cycle) blood samples. a–c Flow cytometry analyses of changes in circulating cell populations in shorter and longer survivors following treatment with entinostat and pembrolizumab. Gating strategies can be found in Supplementary Fig. 5. (a) Graphs showing the frequency of CD3 + lymphocytes (left), CD14 + monocytes (middle), and CD33 + neutrophils (right)...
AI algorithm matches cardiologists’ expertise, while explaining its decisions
by Elizabeth Fernandez, University of California, San Francisco Credit: Pixabay/CC0 Public Domain Clinicians rely daily on electrocardiograms (ECG) to detect common cardiovascular conditions, but accurate diagnoses require high levels of expertise. In a new study that reviewed nearly 1 million ECGs from 365,000 adults, an artificial intelligence algorithm exceeded the performance of a widely available commercial...
Possible viable treatment for human brain cancer
by Texas A&M University Dr. Beth Boudreau, assistant professor of neurology at Texas A&M’s College of Veterinary Medicine & Biomedical Sciences. Credit: Texas A&M College of Veterinary Medicine & Biomedical Sciences A team of researchers at Texas A&M University, Northwestern University, and ImmunoGenesis has discovered a treatment for glioblastoma that has promising implications for the human version of...
The risk of developing a disease linked to genetics tends to decrease with age
PLOS IMAGE: THE BEAUTY OF OLD AGE CREDIT: VINOTH CHANDAR, FLICKR People often get sicker as they grow older, but new research from Gil McVean of the University of Oxford and colleagues finds that the impact of a person’s genes on their risk of getting sick actually wanes with age. The researchers published their new...
‘ASCENT’ makes it easier to study the electrical stimulation of nerves
by Duke University The ASCENT tool models how nerves can respond to electrical stimulation from custom electrodes. Nerve fibers appear in red and blue, and the custom electrodes appear in gray. The bottom graphic shows how the nerves appear when they are activated. Credit: Eric Musselman, Duke University Biomedical engineers at Duke University have developed an...
New ultrasound scanner may eliminate need for invasive cranial surgical procedures
by Christina Benjaminsen, Norwegian University of Science and Technology Elevated intracranial pressure,; or pressure in the brain, can cause permanent damage. There is a significant market for a device that can detect and messure increased pressure easily and quickly without surgery, says Selbekk. Here he demonstrates the technology. Credit: Ole Martin Wold A new invention may...
Increased Risk for Hospitalization, Death with Parkinson’s Drug
Pimavanserin, a novel antipsychotic drug used to manage hallucinations and delusions in Parkinson’s disease, may lead to increased hospitalizations and deaths, according to a new study. A retrospective cohort study of elderly patients with Parkinson’s disease who were in long-term care facilities found that the use of pimavanserin (Nuplazid) was associated with an increased risk of...
As diabetes prevalence rises in children and adults, screening age drops to 35 for overweight adults
By Elizabeth Cooney FRED DUFOUR/AFP/GETTY IMAGES The age at which adults who are overweight or obese should be screened for type 2 diabetes is going down while the prevalence of both forms of the disease is going up among children and adolescents — two developments reported Tuesday that signal a growing burden of these chronic health...
qBrain: Mapping out brain similarities and differences
Cold Spring Harbor Laboratory (CSHL) Associate Professor Pavel Osten and his lab map brain connections and catalog different cell types throughout the brain in a quantitative brain-wide (qBrain) catalog. qBrain combines several techniques developed by CSHL and other scientists to label, preserve, image, visualize, count automatically, and trace cells. With these methods, the researchers can standardize a 3D map of the...
Shorter weekly course of rifapentine-isoniazid associated with much higher treatment completion rates compared to longer daily course
Below please find summaries of new articles that will be published in the next issue of Annals of Internal Medicine. The summaries are not intended to substitute for the full articles as a source of information. This information is under strict embargo and by taking it into possession, media representatives are committing to the terms of the...