Some people recover from COVID-19 quite easily, while others suffer terrible consequences or even die. This, of course, is related to the overall condition of your body, but there are other factors at play as well. For example, scientists researchers from the University of Edinburgh with international partners have discovered 13 DNA sequences that are associated with...
Chronobiology – timing processes in tissues
CHARITÉ – UNIVERSITÄTSMEDIZIN BERLIN The body’s circadian clocks enable organs and organ systems to function according to finely tuned daily rhythms. In humans and other mammals, these circadian rhythms are controlled by an area of the brain known as the hypothalamus. Researchers from Charité – Universitätsmedizin Berlin have deciphered an additional, previously unknown mechanism that...
Heart cell protein could lead to new treatments for heart failure and recovery
by University of Utah Health Sciences Credit: CC0 Public Domain A protein that helps regulate calcium signaling within heart cells could play a key role in preventing chronic heart failure, according to an international study led by University of Utah Health scientists. The researchers say disruption in the signaling pathway for this protein, VDAC2, causes severe impairment of...
Discovery points to ketamine’s long-term antidepressant effects
by Vanderbilt University 3-D model of Ketamine. Credit: Wikipedia Building on recent research confirming how ketamine induces rapid antidepressant action, Professor of Pharmacology Lisa Monteggia and her collaborators show how the molecular mechanism of the gene MeCP2 and associated synaptic adaptability is critical to the long-term antidepressant effects of ketamine. While MeCP2 has been shown to...
Synthetic tissue model with blood vessels developed
by Max Planck Society A synthetic hydrogel in which endothelial cells (pink cell nuclei) form new blood vessels that grow from a parent blood vessel (upright on the left). These form cavities connected to the parent vessel. Here, the vessels were perfused with a liquid containing fluorescent beads (yellow). The beads flow into the new vessels...
Benefits of neurofeedback for those with ADHD mainly due to unexpected factors
by Elsevier Credit: CC0 Public Domain The economic burden of providing special education and training for a child diagnosed with ADHD (attention-deficit/hyperactivity disorder) is estimated to cost the average American family five times as much as a child without ADHD. Such cost considerations force many families to focus on the remission of the condition through prescribed...
Researchers develop ‘dimmer switch’ to help control gene therapy
by Children’s Hospital of Philadelphia Credit: CC0 Public Domain In a major advancement in the field of gene therapy for rare and devastating diseases, researchers at Children’s Hospital of Philadelphia (CHOP) have developed a “dimmer switch” system that can control levels of proteins expressed from gene therapy vectors. The system is based on alternative RNA splicing using an...
Brain cells in Alzheimer’s patients consume resources essential to neurotransmission
by Weber Shandwick Worldwide Credit: Public Domain Alzheimer’s disease (AD), the most common type of dementia, causes the death of neurons and leads to the shrinking of the brain. Patients with AD will eventually experience gradual deterioration in memory, thinking, behavior, and the ability to perform everyday activities. Yet, scientists do not fully understand what causes...
Ancient herbal medicine may offer relief to veterans with Gulf War Illness
by University of South Carolina Figure 1. Gulf War (GW) chemical exposure results in alteration of mouse gut bacteriome, while andrographolide (AG) treatment helps in restoration of normal microbiome. (A) The relative abundance of the bacteriome is presented by group average at the phylum level for CONTROL (mice treated with vehicle only), GWT (GW chemical exposed...
Study suggests postpartum depression differs from major depression
by University of Otago Credit: CC0 Public Domain Women with postpartum depression experience smell differently than other women, a University of Otago study has found. Lead author Dr. Mei Peng, of the Department of Food Science, says the findings add further evidence to the growing argument that postpartum depression is different from major depression, and requires...