Month: <span>September 2021</span>

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Resolving protein errors could lead to healthier and longer lives
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Resolving protein errors could lead to healthier and longer lives

DNA defects are linked to cancer and may be primary reasons for aging. However, scientists argue that protein errors are responsible for some negative health changes as well. Researchers at UCL conducted experiments with simple model organisms and found that correcting protein production errors leads to improvements in both health and lifespan. Fruit flies are often used...

New cell type in human skin discovered to contribute to inflammatory skin diseases like atopic dermatitis and psoriasis
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New cell type in human skin discovered to contribute to inflammatory skin diseases like atopic dermatitis and psoriasis

AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (A*STAR) SINGAPORE IMAGE: IMMUNOFLUORESCENCE LABELING OF HEALTHY AND PSORIATIC PATIENT SKIN. DOTTED LINE SHOWS THE DERMAL–EPIDERMAL JUNCTION. HLA-DR: GREEN, GLUT3 (SLC2A3): RED, AND DAPI: BLUE. SCALE BAR = 100 ΜM (LOW MAGNIFICATION) AND 10 ΜM (HIGH MAGNIFICATION). CREDIT: PLEASE CREDIT IMAGE TO A*STAR SINGAPORE IMMUNOLOGY NETWORK (SIGN) AND SKIN...

How we age, as told by spit
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How we age, as told by spit

OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY (OIST) GRADUATE UNIVERSITY IMAGE: THE GRAPH ABOVE SHOWS THAT THE AGE OF A PERSON CAN BE ROUGHLY IDENTIFIED BY MEASURING ONLY FOUR METABOLITES IN THEIR SALIVA. THE BLUE DOTS EACH REPRESENT ONE PERSON IN THE 27-33 AGE GROUP, WHEREAS THE RED DOTS EACH REPRESENT ONE PERSON IN THE 72-80...

B cells of the immune system discovered in the meninges
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B cells of the immune system discovered in the meninges

UNIVERSITY OF MÜNSTER IMAGE: DIFFERENT TYPES OF WHITE BLOOD CELLS FOUND IN THE OUTER LAYER OF THE MENINGES OF MICE. EXAMINING AROUND 3,000 CELLS, SCIENTISTS ANALYSED WHICH GENES ARE ACTIVE IN EVERY SINGLE CELL AND IDENTIFIED 19 DIFFERENT CELL TYPES. ONE DOT CORRESPONDS TO AN INDIVIDUAL CELL. THE CLOSER THE DOTS ARE TO EACH OTHER,...

Study provides new insight into fundamental workings of the immune system in response to therapy to treat skin cancer
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Study provides new insight into fundamental workings of the immune system in response to therapy to treat skin cancer

by  University of Birmingham Credit: CC0 Public Domain New research led by the University of Birmingham suggests that skin cancer patients could have a better prognosis if their T cells send messages from five specific genes in their immune response to drugs given to treat the disease. The research, carried out in mice, cells in the laboratory, and using...

Therapeutic potential of Mozart for medication-resistant epilepsy
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Therapeutic potential of Mozart for medication-resistant epilepsy

by  Nature Publishing Group Credit: Pixabay/CC0 Public Domain Listening to Mozart’s Sonata for Two Pianos in D Major (K448) for at least 30 seconds may be associated with less frequent spikes of epilepsy-associated electrical activity in the brain in people with medication-resistant epilepsy. The findings, which also suggest that positive emotional responses to K448 may contribute...

Cancer cells’ unexpected genetic tricks for evading the immune system
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Cancer cells’ unexpected genetic tricks for evading the immune system

by Howard Hughes Medical Institute Credit: Pixabay/CC0 Public Domain Hundreds of cancer-linked genes play a different role in causing disease than scientists had expected. So-called tumor suppressor genes have long been known to block cell growth, preventing cancerous cells from spreading. Mutations in these genes, scientists believed, thus allow tumors to flourish unchecked. Now, Howard...

MAIT cell activation may play a role in fatal outcomes among severe COVID-19 cases
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MAIT cell activation may play a role in fatal outcomes among severe COVID-19 cases

by  Public Library of Science Project design and overall conclusions of the St George’s, University of London and University of Oxford collaboration on immune parameters of ICU COVID-19 and severe influenza. Credit: Nicholas Provine, Jonathan Youngs, and Paul Klenerman, CC-BY 4.0, creativecommons.org/licenses/by/4.0/) The mortality rate of COVID-19 patients requiring mechanical ventilation is 30-40%, however, the immunological...

Research reveals new treatment strategy for propionic acidemia
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Research reveals new treatment strategy for propionic acidemia

by  St. Jude Children’s Research Hospital From bottom left, clockwise: Paper author Stephen White, DPhil, St. Jude Department of Structural Biology and St. Jude Graduate School of Biomedical Sciences; paper author Richard Lee, Ph.D., St. Jude Department of Chemical Biology and Therapeutics; corresponding author Charles Rock, Ph.D., St. Jude Infectious Diseases; and senior author Suzanne Jackowski, Ph.D., formerly...

Study identifies key risk factors for early COPD among US Hispanic/Latinos
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Study identifies key risk factors for early COPD among US Hispanic/Latinos

by  Brigham and Women’s Hospital Credit: Pixabay/CC0 Public Domain Chronic obstructive pulmonary disease (COPD) is a progressive disorder that is often not diagnosed until a patient is over 60 years old and has substantial airflow obstruction. At this stage, it can be difficult to manage and treat the condition. To identify those at risk and intervene...